… sufficient and appropriate central command for the … muscle by the motor neurons. We will
examine three topics that demonstrate a significant role for central factors in the muscle fatigue …

… controversy about central and peripheral factors in muscle fatigue. Several factors have
contributed to the delay in establishing the role of “central” factors in human muscle fatigue. First, …

… of muscles. Conversely, the central model states that fatigue results from central factors such
… A novel model of integrative central control (ie, the central governor model, CGM) proposes …

… contributions of central and peripheral factors to the development of human muscle fatigue.
… a maximum voluntary isometric contraction (MVC) of the ankle dorsiflexor muscles for 4 min. …

… Fatigue may be caused by factors within the muscle cells (peripheral fatigue) and diminished
activation from the central … activation from the central nervous system (central fatigue). …

… in the muscle fibre (Enoka and … Fatigue associated with factors that reside within the central
nervous system are referred to as central mechanisms, whereas those that affect the muscle …

… Peripheral and Central Fatigue Muscle fatigue is in this review defined as: a failure to maintain
… Voluntary contraction is a complex series of events and fatigue can occur as a result of …

… neuromuscular fatigue and to present the current knowledge of the central and peripheral
factors … that focuses on the mechanisms responsible for the adaption to neuromuscular fatigue. …

… ing 'history' of both muscle length and the discharge frequency of motor units; and thirdly, of
the many factors capable of changing this relationship, muscle fatigue in sustained maximal …

… factors gives the most reliable quantification of central fatigue. In … of peripheral and central
factors to fatigue during a sustained … peripheral fatigue dominates, but central factors become …