Pathophysiology of hepatic encephalopathy: a new look at ammonia
RF Butterworth - Metabolic brain disease, 2002 - Springer
… utilization rates in patients with chronic liver failure. In addition to the … ammonia production,
new approaches to the treatment of hepatic encephalopathy by lowering of brain ammonia …
new approaches to the treatment of hepatic encephalopathy by lowering of brain ammonia …
Blood ammonia levels and hepatic encephalopathy
AH Lockwood - Metabolic brain disease, 2004 - Springer
… with increasing arterial ammonia levels. Encephalopathic participants in this study had
significantly higher brain ammonia metabolic rates than those without encephalopathy. This …
significantly higher brain ammonia metabolic rates than those without encephalopathy. This …
Ammonia: key factor in the pathogenesis of hepatic encephalopathy
RF Butterworth, JF Giguère, J Michaud, J Lavoie… - Neurochemical …, 1987 - Springer
… hepatic coma resulting from fulminant hepatic failure, brain … dying in hepatic coma resulting
from chronic liver disease. In … cirrhotic patient dying in hepatic coma. The nuclei of affected …
from chronic liver disease. In … cirrhotic patient dying in hepatic coma. The nuclei of affected …
The pathophysiologic basis of hepatic encephalopathy: central role for ammonia and inflammation
D Shawcross, R Jalan - Cellular and Molecular Life Sciences CMLS, 2005 - Springer
… concentrations of ammonia may increase the uptake of ammonia in the brain through an …
brain barrier to ammonia [19]. In experimental animals with acute liver failure, brain ammonia …
brain barrier to ammonia [19]. In experimental animals with acute liver failure, brain ammonia …
Ammonia‐lowering strategies for the treatment of hepatic encephalopathy
CF Rose - Clinical Pharmacology & Therapeutics, 2012 - Wiley Online Library
… Hyperammonemia leads to neurotoxic levels of brain ammonia and is a major factor
involved in the pathogenesis of hepatic encephalopathy (HE). Ammonia-lowering treatments …
involved in the pathogenesis of hepatic encephalopathy (HE). Ammonia-lowering treatments …
Hepatic encephalopathy
J Córdoba, B Mínguez - Seminars in liver disease, 2008 - thieme-connect.com
… plasma ammonia, measures to reduce brain edema, and liver-support devices. … Cerebral
ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy…
ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy…
Pathogenesis of hepatic encephalopathy: role of ammonia and systemic inflammation
DR Aldridge, EJ Tranah, DL Shawcross - Journal of clinical and …, 2015 - Elsevier
… The syndrome we refer to as Hepatic Encephalopathy (HE) was first characterized by a …
away from the liver, induced elevated blood and brain ammonia concentrations in association …
away from the liver, induced elevated blood and brain ammonia concentrations in association …
Pathogenesis of Hepatic Encephalopathy-with Special Reference to the Roles of Ammonia
CO WALKER, S SCHENKER - The American journal of clinical nutrition, 1970 - Elsevier
… As regards ammonia, the only likely toxin meaningfully … brain, probably at the site of cerebral
ammonia detoxication, ie, at the α-ketoglutarate-glutamate-glutamine level. In acute coma, …
ammonia detoxication, ie, at the α-ketoglutarate-glutamate-glutamine level. In acute coma, …
[HTML][HTML] Hepatic encephalopathy
RF Butterworth - Alcohol Research & Health, 2003 - ncbi.nlm.nih.gov
… One of the main causes of brain dysfunction in patients with hepatic encephalopathy (HE)
is the accumulation of ammonia in the blood, which the patient’s liver, damaged by alcoholic …
is the accumulation of ammonia in the blood, which the patient’s liver, damaged by alcoholic …
Ammonia and its role in the pathogenesis of hepatic encephalopathy
PJ Parekh, LA Balart - Clinics in liver disease, 2015 - liver.theclinics.com
… ammonia levels adapt by increasing permeability surface area (PSA). Cerebral ammonia …
The increased PSA allows ammonia to diffuse across the blood-brain barrier more freely …
The increased PSA allows ammonia to diffuse across the blood-brain barrier more freely …
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