Clonal expansion and somatic hypermutation of V (H) genes of B cells from cerebrospinal fluid in multiple sclerosis.
Y Qin, P Duquette, Y Zhang, P Talbot… - The Journal of …, 1998 - Am Soc Clin Investig
… clonal expansion was identified in 3 of 15 OND. The nucleotide sequences of VH genes from
clonally expanded … is a high frequency of clonally expanded B cells that have properties of …
clonally expanded … is a high frequency of clonally expanded B cells that have properties of …
Multiple sclerosis: Brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood
C Skulina, S Schmidt, K Dornmair… - Proceedings of the …, 2004 - National Acad Sciences
… + clonal expansions shared between the different tissue compartments could indicate that the
sizes of CD4 + expansions are smaller than those of CD8 + expansions… clonal expansions …
sizes of CD4 + expansions are smaller than those of CD8 + expansions… clonal expansions …
Single-cell repertoire analysis demonstrates that clonal expansion is a prominent feature of the B cell response in multiple sclerosis cerebrospinal fluid
GP Owens, AM Ritchie, MP Burgoon… - The Journal of …, 2003 - journals.aai.org
… Our goal was to evaluate the extent of B cell clonal expansion within the … clonally related
IgG sequences in MS plaques (8, 9, 10, 11) and CSF (12, 13), we detected clonally expanded B …
IgG sequences in MS plaques (8, 9, 10, 11) and CSF (12, 13), we detected clonally expanded B …
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease
… , we discovered clonally expanded CD8 + T EMRA cells in the cerebrospinal fluid of patients
with … the specificity of clonally expanded TCRs in the cerebrospinal fluid of patients with …
with … the specificity of clonally expanded TCRs in the cerebrospinal fluid of patients with …
[HTML][HTML] Intrathecal B-cell clonal expansion, an early sign of humoral immunity, in the cerebrospinal fluid of patients with clinically isolated syndrome suggestive of …
Y Qin, P Duquette, Y Zhang, M Olek, RR Da… - Laboratory …, 2003 - Elsevier
… In the present study, we have studied B-cell clonal expansion and somatic hypermutation …
clonal expansion are characteristic of the adaptive immune response in the cerebrospinal fluid …
clonal expansion are characteristic of the adaptive immune response in the cerebrospinal fluid …
Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid
GP Owens, JL Bennett, H Lassmann… - Annals of Neurology …, 2009 - Wiley Online Library
… We predict that clonally expanded plasma cells in MS CSF represent the intrathecal … and
clonal selection within the CNS. Supporting this view is a strong link between expanded IgG V-…
clonal selection within the CNS. Supporting this view is a strong link between expanded IgG V-…
Clonally expanded plasma cells in the cerebrospinal fluid of MS patients produce myelin‐specific antibodies
HC von Büdingen, MD Harrer… - European journal of …, 2008 - Wiley Online Library
… Clonally expanded plasma cells (cePC) and their presumed products, oligoclonal immunoglobulin
G bands (OCB), are characteristic findings in the cerebrospinal fluid (CSF) of patients …
G bands (OCB), are characteristic findings in the cerebrospinal fluid (CSF) of patients …
[HTML][HTML] High-dimensional investigation of the cerebrospinal fluid to explore and monitor CNS immune responses
… The cerebrospinal fluid (CSF) features a unique immune cell composition … clonally expanded
T and B cells in the CSF in the autoimmune disease multiple sclerosis; clonally expanded …
T and B cells in the CSF in the autoimmune disease multiple sclerosis; clonally expanded …
Clonally expanded plasma cells in the cerebrospinal fluid of patients with central nervous system autoimmune demyelination produce “oligoclonal bands”
HC Von Büdingen, M Gulati, S Kuenzle… - Journal of …, 2010 - Elsevier
Clonally expanded plasma cells (cePC) and oligoclonal IgG (oligoclonal bands, OCB) in the
cerebrospinal fluid (… We expand these findings by applying anti-idiotypic antibodies to detect …
cerebrospinal fluid (… We expand these findings by applying anti-idiotypic antibodies to detect …
B‐lymphocyte and plasma cell clonal expansion in monosymptomatic optic neuritis cerebrospinal fluid
K Haubold, GP Owens, P Kaur, AM Ritchie… - Annals of …, 2004 - Wiley Online Library
… The CD19+ B-lymphocyte and CD138+ plasma cell repertoires in cerebrospinal fluid from …
cell repertoires from ON cerebrospinal fluid demonstrated significant clonal expansion. Up to …
cell repertoires from ON cerebrospinal fluid demonstrated significant clonal expansion. Up to …
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- multiple sclerosis cerebrospinal fluid
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- cerebrospinal fluid in alzheimer's disease
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- single cell repertoire analysis clonal expansion
- cerebrospinal fluid of ms patients
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- plasma cells in the cerebrospinal fluid