Understanding the HPV integration and its progression to cervical cancer
MA Oyervides-Muñoz, AA Pérez-Maya… - Infection, Genetics and …, 2018 - Elsevier
… HPV integration affect the progression of cervical cancer, … HPV integration, including the
forms and integration sites in the host's genome, as well as the implications that such integration …
forms and integration sites in the host's genome, as well as the implications that such integration …
Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism
… (HPV) integration is a key genetic event in cervical … viral integration detection, we identified
3,667 HPV integration breakpoints in 26 cervical intraepithelial neoplasias, 104 cervical …
3,667 HPV integration breakpoints in 26 cervical intraepithelial neoplasias, 104 cervical …
Non-random integration of the HPV genome in cervical cancer
M Schmitz, C Driesch, L Jansen, IB Runnebaum… - PloS one, 2012 - journals.plos.org
… another cluster of integration sites within the … the integrated HPV DNA. By compiling our
data and published reports 9 genes could be identified which were affected by HPV integration …
data and published reports 9 genes could be identified which were affected by HPV integration …
The role of viral integration in the development of cervical cancer
T Yu, MJ Ferber, TH Cheung, TKH Chung… - Cancer genetics and …, 2005 - Elsevier
… where the sites of HPV integration in cervical tumors are nonrandom and where genes at
or near the sites of integration could play a role in the eventual cervical cancers that develop. …
or near the sites of integration could play a role in the eventual cervical cancers that develop. …
Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site
M Kamal, S Lameiras, M Deloger, A Morel… - … journal of cancer, 2021 - nature.com
… This is to our knowledge the first study assessing the prognostic value of HPV integration
in a prospectively annotated CC cohort, which detects a hotspot of HPV integration at …
in a prospectively annotated CC cohort, which detects a hotspot of HPV integration at …
[HTML][HTML] Integrated genomic and molecular characterization of cervical cancer
Cancer Genome Atlas Research Network - Nature, 2017 - ncbi.nlm.nih.gov
… significantly mutated genes in cervical cancer. We also discovered … HPV integration was
observed in all HPV18-related cases … -like cervical cancers, comprised predominantly of HPV-…
observed in all HPV18-related cases … -like cervical cancers, comprised predominantly of HPV-…
Characteristic of HPV integration in the genome and transcriptome of cervical cancer tissues
W Li, Y Qi, X Cui, Q Huo, L Zhu, A Zhang… - BioMed research …, 2018 - Wiley Online Library
… gain insights into the HPV integration sites in DNA and RNA samples of cervical cancer. It
had provided … from the perspective of HPV integration in the HPV-associated cervical cancers. …
had provided … from the perspective of HPV integration in the HPV-associated cervical cancers. …
Multi-omics characterization of silent and productive HPV integration in cervical cancer
J Fan, Y Fu, W Peng, X Li, Y Shen, E Guo, F Lu, S Zhou… - Cell Genomics, 2023 - cell.com
… (A) Distribution of genomic and transcriptional HPV integration in the human genome in 98
cervical cancers. The outer circle represents the human genome, with chromosomes labeled …
cervical cancers. The outer circle represents the human genome, with chromosomes labeled …
[HTML][HTML] Integrating HPV vaccination programs with enhanced cervical cancer screening and treatment, a systematic review
C Wirtz, Y Mohamed, D Engel, A Sidibe, M Holloway… - Vaccine, 2022 - Elsevier
… to integrate HPV vaccination with cervical cancer … integration of HPV vaccination with cervical
cancer screening has been implemented in LMICs, determine whether and how integration …
cancer screening has been implemented in LMICs, determine whether and how integration …
Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer
L Zhou, Q Qiu, Q Zhou, J Li, M Yu, K Li, L Xu… - Nature …, 2022 - nature.com
… genes in cervical cancer. Finally, we reveal the spatial relationship of HPV integration and its
… well as their functional consequences in cervical cancer. These findings provide insight into …
… well as their functional consequences in cervical cancer. These findings provide insight into …
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