Erlotinib and gefitinib responsiveness in head and neck cancer cell lines—a comparing analysis with cetuximab

S Hartmann, N Neckel, A Seher, G Mutzbauer… - Clinical oral …, 2016 - Springer
… The objective of this study is to examine the efficacy of erlotinib and gefitinib with respect
to epidermal growth factor (EGF) and cetuximab response in head and neck cancer cell lines. …

Phase I/II trial of cetuximab and erlotinib in patients with lung adenocarcinoma and acquired resistance to erlotinib

YY Janjigian, CG Azzoli, LM Krug, LK Pereira… - Clinical cancer …, 2011 - AACR
… Laboratory and clinical data suggest that these tumors still depend on signaling through the
… of a trial combining erlotinib and cetuximab in patients with acquired resistance to erlotinib. …

Combining Erlotinib and Cetuximab Is Associated with Activity in Patients with Non–Small Cell Lung Cancer (Including Squamous Cell Carcinomas) and Wild-Type …

JJ Wheler, AM Tsimberidou, GS Falchook… - Molecular cancer …, 2013 - AACR
erlotinib 150 mg oral daily and cetuximab 250 mg/m 2 iv weekly. In summary, erlotinib and
cetuximab … five of 20 patients with non–small cell lung cancer (25%), including individuals with …

[HTML][HTML] Effects of Cetuximab and Erlotinib on the behaviour of cancer stem cells in head and neck squamous cell carcinoma

MFSD Rodrigues, L Gammon, MM Rahman, A Biddle… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… heterogeneity and this is further complicated by cancer stem cells (CSC) shifting between …
the effects of Cetuximab and Erlotinib on the cell sub-populations in HNSCC cell lines. …

[HTML][HTML] Dual EGFR blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation …

V Subbiah, EI Dumbrava, Y Jiang, KZ Thein… - … hematology & oncology, 2020 - Springer
… a phase I study combining erlotinib, cetuximab, and … tumors (excluding colorectal and
non-small cell lung cancers) were analyzed for safety, toxicity profile, and response. Anti-tumor

Description and management of cutaneous side effects during cetuximab or erlotinib treatments: a prospective study of 30 patients

E Roé, MPG Muret, E Marcuello, J Capdevila… - Journal of the American …, 2006 - Elsevier
… The aim of this study was to evaluate the incidence of cutaneous reactions to cetuximab
and erlotinib, and to describe their clinical features and therapeutic management. …

… using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer

AJ Weickhardt, TJ Price, G Chong, V Gebski… - Journal of clinical …, 2012 - ascopubs.org
cetuximab and erlotinib on the growth of colon cancer cells in … data showed synergy between
cetuximab and erlotinib, we … cancer—the Dual Targeting of EGFR Using Cetuximab and …

Erlotinib is a viable treatment for tumors with acquired resistance to cetuximab

TM Brand, EF Dunn, M Iida, RA Myers… - Cancer Biology & …, 2011 - Taylor & Francis
… To further investigate the growth delay effect of cetuximab-resistant tumors by erlotinib we …
tumor samples. We first measured cell proliferation (Ki67) in tumors treated with erlotinib (T1, …

Combined Erlotinib and Cetuximab overcome the acquired resistance to epidermal growth factor receptors tyrosine kinase inhibitor in non-small-cell lung cancer

M Wang, J Zhao, LM Zhang, H Li, JP Yu… - Journal of cancer …, 2012 - Springer
Erlotinib and Cetuximab on T790M and L858R mutation lung cancer cells lines (H1975),
in the primary NSCLC cells … -resistant EGFR mutations human tumor xenograft model (H1975). …

Dual inhibition of the epidermal growth factor receptor pathway with cetuximab and erlotinib: a phase I study in patients with advanced solid malignancies

MJ Guarino, CJ Schneider, MA Hosford… - The …, 2009 - academic.oup.com
… cohort would validate cetuximab at a dose of 250 mg/m 2 weekly plus erlotinib at 150 mg
daily as … where either cetuximab or erlotinib is known to be active, including colorectal cancer, …