Cetuximab: a review of its use in squamous cell carcinoma of the head and neck and metastatic colorectal cancer

SKA Blick, LJ Scott - Drugs, 2007 - Springer
… mCRC, cetuximab plus irinotecan improved ORR more than cetuximab monotherapy in a …
(OS) between cetuximab plus irinotecan and cetuximab monotherapy in oxaliplatin-refractory …

The role of cetuximab in the treatment of squamous cell cancer of the head and neck

B Burtness - Expert opinion on biological therapy, 2005 - Taylor & Francis
… the head and neck, as is cetuximab monotherapy. When cetuximab is added to cisplatin
monotherapy in … squamous cell carcinoma of the head and neck, the objective response rate is …

Cetuximab-containing combinations in locally advanced and recurrent or metastatic head and neck squamous cell carcinoma

M Taberna, M Oliva, R Mesía - Frontiers in oncology, 2019 - frontiersin.org
… In recurrent/metastatic (R/M) HNSCC, we had to choose between monotherapy and
polychemotherapy until the results from the EXTREME trial. The addition of cetuximab to first-line …

Cetuximab monotherapy is active in patients (pts) with platinum-refractory recurrent/metastatic squamous cell carcinoma of the head and neck (SCCHN): results of a …

J Trigo, R Hitt, P Koralewski, E Diaz-Rubio… - Journal of Clinical …, 2004 - ascopubs.org
… to investigate the efficacy of cetuximab as monotherapy in pts with … Cetuximab was given at
an initial dose of 400 mg/m 2 , … switch to the combination of cetuximab with the same platinum …

Overview of the efficacy of cetuximab in recurrent and/or metastatic squamous cell carcinoma of the head and neck in patients who previously failed platinum‐based …

JB Vermorken, RS Herbst, X Leon… - … Journal of the …, 2008 - Wiley Online Library
cetuximab monotherapy or cetuximab in combination with cisplatin or carboplatin. The
principles of the study designs and their key inclusion and exclusion criteria are presented in …

Concurrent cetuximab versus platinum‐based chemoradiation for the definitive treatment of locoregionally advanced head and neck cancer

C Tang, C Chan, W Jiang, JD Murphy… - Head & …, 2015 - Wiley Online Library
… treated with cetuximab monotherapy to 125 … cetuximab monotherapy in the available
retrospective series. Both the MKSCC study and this study administered cetuximab monotherapy to …

The contribution of cetuximab in the treatment of recurrent and/or metastatic head and neck cancer

MA Tejani, RB Cohen, R Mehra - Biologics: Targets and Therapy, 2010 - Taylor & Francis
Cetuximab is also active as monotherapy in patients whose cancer has progressed on … on
cetuximab monotherapy in this trial were given the option to receive cetuximab and cisplatin; …

Cetuximab in metastatic or recurrent head and neck cancer: the EXTREME trial

F Rivera, A García-Castaño, N Vega… - Expert review of …, 2009 - Taylor & Francis
… FDA approved the indication of cetuximab monotherapy in patients with recurrent … cetuximab.
The results from the EXTREME trial (and from other studies of cetuximab in head and neck

Cetuximab in the treatment of head and neck cancer

J Bernier - Expert review of anticancer therapy, 2006 - Taylor & Francis
Cetuximab monotherapy is also approved in the USA for the treatment of recurrent and/or …
study comparing cetuximab monotherapy with other chemotherapeutic agents in this setting. …

Immunogenomic correlates of response to cetuximab monotherapy in head and neck squamous cell carcinoma

DL Faden, F Concha‐Benavente, AB Chakka… - Head & …, 2019 - Wiley Online Library
… Mechanisms of resistance to cetuximab in HNSCC are poorly understood. … cetuximab
therapy, we recently conducted a prospective clinical trial of neoadjuvant cetuximab monotherapy (…