Recent clinical trials for the etiological treatment of chronic Chagas disease: advances, challenges and perspectives

JA Urbina - Journal of Eukaryotic Microbiology, 2015 - Wiley Online Library
… the acute phase of Chagas disease and the importance of etiological treatment in that stage
… of the parasite in the pathogenesis of chronic Chagas disease was the subject of decades of …

[HTML][HTML] Advances in the treatment of Chagas disease: Promising new drugs, plants and targets

P García-Huertas, N Cardona-Castro - Biomedicine & Pharmacotherapy, 2021 - Elsevier
… therapeutic alternatives to treat Chagas disease, though … to treat Chagas disease and
benefit the populations it affects. … have been made to improve the Chagas disease treatment. …

Treatment of Chagas disease in the United States

S Meymandi, S Hernandez, S Park… - Current treatment …, 2018 - Springer
… Diagnostic process of the center of excellence for Chagas disease at olive view-UCLA
medical center. Patients eligible for treatment are first tested at a commercial laboratory. If that …

Current advances in drug discovery for Chagas disease

CB Scarim, DH Jornada, RC Chelucci… - European journal of …, 2018 - Elsevier
… discovery approaches used for Chagas disease, as well as some drug targets explored in
the last few years. In this context, we have presented the current advances in the medicinal …

New insights in Chagas' disease treatment

JA Urbina - Drugs Future, 2010 - access.portico.org
… Among these compounds, the most advanced candidate for new specific treatment for
Chagasdisease is the structural itraconazole analogue posaconazole, due to its remarkable …

[HTML][HTML] Experimental and clinical treatment of Chagas disease: a review

PAS Junior, I Molina, SMF Murta… - The American journal …, 2017 - ncbi.nlm.nih.gov
Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
broad range of triatomines and mammalian species, including man. It afflicts 8 million people …

Specific treatment of Chagas disease: current status and new developments

JA Urbina - Current opinion in infectious diseases, 2001 - journals.lww.com
… hypothesis that Chagas disease should be treated as a parasitic, not an autoimmune, disease.
… development of sterol biosynthesis inhibitors for the treatment of human Chagas disease. …

Advances in Chagas disease chemotherapy

PMM Guedes, JLR Fietto, M Lana… - Anti-Infective Agents in …, 2006 - ingentaconnect.com
… of the early diagnosis and treatment in Chagas disease. CURRENT CLINICAL TREATMENT
OF CHAGAS DISEASE Specific chemotherapy of Chagas disease has been developed …

Advances and progress in Chagas disease drug discovery

LG Ferreira, MT de Oliveira… - Current topics in …, 2016 - ingentaconnect.com
… recent advances in Chagas disease drug discovery. … treatment of Chagas disease is aimed
at eradicating the parasite from the patient, thereby preventing the evolution of the disease

Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches

JA Urbina - Acta tropica, 2010 - Elsevier
… or Chagas disease is presented, including controversies on the pathogenesis of the disease,
the … , poised to enter clinical trials for chronic Chagas disease in the short term; inhibitors of …