… In the search for alternatives to treat Chagas disease, an increasing number of drug … A
new era for chagas disease drug discovery? Progress in Medicinal Chemistry, 54: 185-…

… drug discovery and development efforts to discover better and safer treatments. In this article
we will review past and current findings on drug discovery … treatments for Chagas disease in …

… Drug discovery for Chagas disease: impact of different host … Drug discovery for Chagas
disease: impact of different host … ) have been used in several drug discovering programs as likely …

… will discuss the treatment of human Chagas disease with the drugs currently in use, as well
as the potential new drugs under trial and innovative strategies for treating Chagas disease. …

… The availability of transgenic parasites is already having a positive impact on drug discovery
against Chagas disease. It will be of great importance to the drug discovery process in the …

… , new drugs are urgently needed. This Review considers the relevant aspects related to
the lack of drugs for Chagas disease, resumes the advances in tools for drug discovery, and …

… Introduction: Endemic in Latin America, Chagas disease is now becoming a serious global
… for Chagas disease, either on their own or in combination with the currently available drugs. …

… b is an important advance for drug discovery in the field. … ) as a novel drug target for Chagas
disease drug discovery. The … a new molecular target for Chagas disease drug discovery, the …

… For in vitro models for Chagas disease drug discovery and development, what is known
and what is needed? This discussion focused on parasite forms and stocks, mammalian cell …

Chagas disease is caused by infection with the insect-transmitted protozoan Trypanosoma
cruzi, and is the most important parasitic infection in Latin America. The current drugs, …