Current drug therapy and pharmaceutical challenges for Chagas disease

J Bermudez, C Davies, A Simonazzi, JP Real, S Palma - Acta tropica, 2016 - Elsevier
… will discuss the treatment of human Chagas disease with the drugs currently in use, as well
as the potential new drugs under trial and innovative strategies for treating Chagas disease. …

Current and developing therapeutic agents in the treatment of Chagas disease

W Apt - Drug design, development and therapy, 2010 - Taylor & Francis
… of human Chagas disease in its different stages with the drugs currently in use. … Current drug
therapy … etiological treatment of Chagas disease will include combination of drugs to obtain …

[HTML][HTML] Current trends in the pharmacological management of Chagas disease

V Ribeiro, N Dias, T Paiva, L Hagström-Bex… - … : Drugs and Drug …, 2020 - Elsevier
… In the present study, a literature review of the currently adopted therapy, its concomitant
combination with other drugs, and potential future treatments for CD was performed, considering …

[HTML][HTML] Perspectives for a new drug candidate for Chagas disease therapy

MNC Soeiro - Memorias do Instituto Oswaldo Cruz, 2022 - SciELO Brasil
… experimental models for drug screening and development for Chagas disease. Mem Inst …
of drugs for the treatment of Chagas disease: what shows the most promise? Expert Opin Drug

Efficacy and safety of chagas disease drug therapy and treatment perspectives

WH Kawaguchi, LB Cerqueira, MM Fachi… - Chagas Disease …, 2018 - books.google.com
… on the evaluation of efficacy and safety of the current drug therapy, will be properly addressed
in this chapter. In addition, a review of new pharmacological therapies will be discussed. …

[HTML][HTML] Experimental and clinical treatment of Chagas disease: a review

PAS Junior, I Molina, SMF Murta… - The American journal …, 2017 - ncbi.nlm.nih.gov
Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
broad range of triatomines and mammalian species, including man. It afflicts 8 million people …

Treatment of Chagas disease

W Apt - American Trypanosomiasis Chagas Disease, 2017 - Elsevier
… It is important to point out that the drugs used in Chagas disease therapy must have an
effect on the intracellular amastigote forms, which are the reproductive … Current drug therapy

[HTML][HTML] Drug discovery for chagas disease: A viewpoint

JM Kratz - Acta tropica, 2019 - Elsevier
Chagas disease is a neglected tropical disease caused by the protozoan parasite … drugs,
benznidazole and nifurtimox, are currently available for the treatment of Chagas disease and …

[HTML][HTML] Challenges in Chagas disease drug development

AF Francisco, S Jayawardhana, F Olmo, MD Lewis… - Molecules, 2020 - mdpi.com
… The protozoan parasite Trypanosoma cruzi causes Chagas disease, an important public
health problem throughout Latin America. Current therapeutic options are characterised by …

Challenges in Chagas disease drug discovery: a review

R Paucar, E Moreno-Viguri… - Current Medicinal …, 2016 - ingentaconnect.com
… safe and affordable drugs to fight against this complex disease. … promising drugs for the
treatment of Chagas disease during the … drug therapy and pharmaceutical challenges for Chagas