Therapeutical approaches under investigation for treatment of Chagas disease

MT Bahia, LF Diniz, VCF Mosqueira - Expert opinion on …, 2014 - Taylor & Francis
treatments for Chagas disease. … Chagas disease. However, despite some progress being
made in preclinical studies, there is yet to be an ideal drug or formulation for human treatment. …

Current and developing therapeutic agents in the treatment of Chagas disease

W Apt - Drug design, development and therapy, 2010 - Taylor & Francis
… The latter may be the drug to treat Chagas disease in the future when all the investigations
… Based on this information, we will discuss the treatment of human Chagas disease in its …

[HTML][HTML] Experimental and clinical treatment of Chagas disease: a review

PAS Junior, I Molina, SMF Murta… - The American journal …, 2017 - ncbi.nlm.nih.gov
Chagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi that infects a
treatment of this infection have been benznidazole (BZ) and nifurtimox (NFX). Treatment with …

Treatment of Chagas disease

W Apt - American Trypanosomiasis Chagas Disease, 2017 - Elsevier
… In patients with acute Chagas disease treated with allopurinol … in patients with chronic Chagas
disease treated with 900 mg/day … in patients with chronic Chagas disease, and in some of …

Specific treatment of Chagas disease: current status and new developments

JA Urbina - Current opinion in infectious diseases, 2001 - journals.lww.com
… hypothesis that Chagas disease should be treated as a parasitic, not an autoimmune, disease.
… development of sterol biosynthesis inhibitors for the treatment of human Chagas disease. …

Review of pharmacological options for the treatment of Chagas disease

F Lascano, F García Bournissen… - British journal of clinical …, 2022 - Wiley Online Library
… Tropical Diseases 20 announced plans for the elimination or control of Chagas disease
by 2020, current estimates indicate that less than 1% of CD-infected patients are treated and …

[HTML][HTML] Advances in the treatment of Chagas disease: Promising new drugs, plants and targets

P García-Huertas, N Cardona-Castro - Biomedicine & Pharmacotherapy, 2021 - Elsevier
… therapeutic alternatives to treat Chagas disease, though … to treat Chagas disease and
benefit the populations it affects. … have been made to improve the Chagas disease treatment. …

[HTML][HTML] Drug discovery for chagas disease: A viewpoint

JM Kratz - Acta tropica, 2019 - Elsevier
Chagas disease is a neglected tropical disease caused by … available for the treatment of
Chagas disease and both have … preclude the development of new treatments, some of them …

Current drug therapy and pharmaceutical challenges for Chagas disease

J Bermudez, C Davies, A Simonazzi, JP Real, S Palma - Acta tropica, 2016 - Elsevier
… of Chagas disease are limited to case detection and treatment, … will discuss the treatment of
human Chagas disease with the … trial and innovative strategies for treating Chagas disease. …

[PDF][PDF] Treatment of chronic Chagas' disease with itraconazole and allopurinol.

W Apt, X Aguilera, A Arribada, C Pérez… - The American journal …, 1998 - researchgate.net
… Table 3 shows the ECG changes in 103 chagasic disease patients with cardiopathy
treated with either itraconazole or allopurinol. The ECG returned to normal in 39 cases (36.5%). …