… measures and reduce the burden of cancer, we reflect here on the role of carcinogenicity …
advances in carcinogenicity assessment and their potential to help the fight against cancer. …

… Testing aims to develop and apply new methods for assessment of potential carcinogenic
risk to humans from various chemicals. The Workshop represents a major cooperative scientifi …

… Carcinogenicity assessment of any compound is a laborious … contingent on several challenges
concerning the inadequacy … carcinogen by International Agency for Research on Cancer (…

… conventional rodent cancer bioassay and for assessing human health … cancer bioassays
with GM mice for assessing the potential health risks associated with exposure to carcinogenic …

… The workshop sessions addressed key challenges in carcinogenicity assessment related
to … and assessing mechanisms and MoAs relevant to human cancers. At present, full …

… carcinogenicity models to be developed, especially ones that are more directly applicable to
predicting the risk for cancer in … The use of these KCs to identify carcinogens is challenging …

… of rodent bioassay data to predicting human cancer risks have emerged, with notable
challenges in both anticipating the potential human cancer target organs and in quantitative risk …

… , and then the longer or more challenging tests are used only on … higher the number of
putatively cancer hazard processes a … in vitro methods for assessing the carcinogenic potential of …

… Further discussion of opportunities to advance the field of toxicogenomics and implement
near-term tools/solutions for contemporary challenges in cancer risk assessment follows below…

… in vitro approaches to testing and assessment. The format is … be conceptually similar to the
challenge of integrating relevant in … of rodent forestomach tumors in cancer risk assessment. …