Background : Guidelines strongly recommend patients with heart failure with reduced ejection
fraction (HFrEF) be treated with multiple medications proven to improve clinical outcomes, …

… In this study from the CHAMP-HF (Change the Management of Patients with Heart Failure)
registry, we describe changes in left ventricular ejection fraction over time in routine practice. …

… CHAMP‐HF was a registry of outpatients with heart failure (HF) and LVEF ≤40%. Enrolled
participants completed the Kansas City Cardiomyopathy Questionnaire‐12 (KCCQ‐12) at …

… Heart failure with reduced ejection fraction (HFrEF) is associated with significant morbidity
and mortality (1). Over the past few decades, advances in medical therapy have resulted in a …

… PARADIGM ‐ HF trial with those in the CHAMP ‐HF (Change … HF with reduced ejection
fraction. Patients in the PARADIGM ‐ HF trial (n=8442) were similar to those in the CHAMP ‐ HF …

… One of the primary treatment goals for patients with heart failure with reduced ejection
fraction (HFrEF) is to optimize their health status by alleviating their symptoms and improving …

… Eligible patients had diagnoses of chronic heart failure (HF), left ventricular ejection fraction
(EF) ≤ 40% on the most recent imaging within 12 months of enrollment, and were receiving …

… used data from the CHAMP-HF (Change the Management of Patients With HF) registry, …
ejection fraction ≤40% within 1 year of enrollment), (3) prescribed oral pharmacotherapy for HF …

BACKGROUND: The foundation for managing heart failure with reduced ejection fraction (HFrEF)
is adherence to guideline-directed medical therapy. Finding an association between …

… The present analysis included participants enrolled in the CHAMP-HF registry through
March 2020. The design of the CHAMP-HF registry has been previously described. CHAMP-HF …