The biogenesis, biology and characterization of circular RNAs

LS Kristensen, MS Andersen, LVW Stagsted… - Nature reviews …, 2019 - nature.com
… (RNase) R treatment to identify the band corresponding to the circular RNA (circRNA) of
interest. The probe may target the circular and the linear transcript of a gene (left) or specifically …

Characterization of circular RNAs

Y Zhang, L Yang, LL Chen - Long non-coding RNAs: Methods and …, 2016 - Springer
circular RNA characterization (Fig. 1), from the fractionation of non-polyadenylated RNAs from
total RNAs, to the enrichment of circular RNAs … protocol to characterize circular RNAs , and …

[HTML][HTML] Circular RNAs: Characterization, cellular roles, and applications

CX Liu, LL Chen - Cell, 2022 - cell.com
… Depending on their localization and specific interactions with DNA, RNA, and proteins, circular
RNAs … In this review, we discuss approaches used in circular RNA studies and the current …

[HTML][HTML] Characterization of circular RNAs in human, mouse and rat hearts

S Werfel, S Nothjunge, T Schwarzmayr… - Journal of molecular and …, 2016 - Elsevier
Deep sequencing techniques and advanced data analysis methods recently enabled the
characterization of thousands of circular RNA isoforms (circRNAs) from a number of tissues …

Detecting and characterizing circular RNAs

WR Jeck, NE Sharpless - Nature biotechnology, 2014 - nature.com
… , as their study through traditional methods of RNA analysis has been difficult. Now, novel …
circular RNA species. Recent studies have revealed thousands of endogenous circular RNAs

Identification and characterization of circular RNAs in zebrafish

Y Shen, X Guo, W Wang - FEBS letters, 2017 - Wiley Online Library
Circular RNAs (circRNAs) are a class of special RNAs that covalently forms a closed loop
in eukaryotes [1-4]. circRNAs were confirmed to be more stable than linear RNAs and to be …

Circular RNAs: isolation, characterization and their potential role in diseases

L Liu, J Wang, R Khanabdali, B Kalionis, X Tai… - RNA biology, 2017 - Taylor & Francis
Circular RNA (circRNA) describes a class of annular RNA molecules comprising one or more
exons. This type of RNA … of a covalently closed circular RNA molecule that was pathogenic …

Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood

S Memczak, P Papavasileiou, O Peters, N Rajewsky - PloS one, 2015 - journals.plos.org
… Strikingly, we observe hundreds of cases where circular RNA isoforms are readily detectable
but the corresponding linear gene products are virtually absent. Thus, blood circRNA …

Comprehensive characterization of circular RNAs in~ 1000 human cancer cell lines

H Ruan, Y Xiang, J Ko, S Li, Y Jing, X Zhu, Y Ye… - Genome medicine, 2019 - Springer
… However, there is no characterization of circular RNAs (… characterize the expression
landscape of circRNAs across ~ 1000 human cancer cell lines from CCLE polyA-enriched RNA-seq …

Expanded identification and characterization of mammalian circular RNAs

JU Guo, V Agarwal, H Guo, DP Bartel - Genome biology, 2014 - Springer
Background The recent reports of two circular RNAs (circRNAs) with strong potential to act
as microRNA (miRNA) sponges suggest that circRNAs might play important roles in …