… and irAEs induced by immune checkpoint inhibitor therapy. Induction of both antitumor …
the antitumor immunity induced by immune checkpoint inhibitor (indicated by the dashed lines). …

… Immune checkpoint inhibitors have the potential to produce durable tumor remission and
induce long standing anti-tumor immunity in a subgroup of breast cancer patients. However, …

… directed against other immune checkpoints are currently under … the implementation of
checkpoint inhibition in breast cancer by … immunity in breast cancer with checkpoint …

… Subsequent data led to approvals of combination strategies of immune checkpoint inhibition
plus agents that target the vascular endothelial growth factor receptor and a shift in the …

… immune checkpoint inhibitors that inhibit checkpoint proteins ( Figure 1 ). The current insights
gained through biomarker analysis of the efficacy of immune checkpoint inhibitors … cancer …

… Immune checkpoint inhibitors have undoubtedly shifted the cancer therapy paradigm.
However, tumors induce a TME that benefits themselves by various mechanisms, and there are …

… Immune-checkpoint inhibitors (ICIs) have emerged as a core pillar of cancer therapy. Nearly
half of all patients with metastatic cancer in economically developed countries are eligible to …

… Combination therapies should be tailored to specific conditions of resistance in a personalized
cancer therapy approach. B2M indicates β2-microglobulin; B7, a family of peripheral …

… cells and, thus, to cancer progression. Citation3,Citation4 We describe cellular receptors …
how immune-checkpoint inhibitors can help overcome T-cell dysfunction in cancer treatment. …

… Immune checkpoint inhibitors (ICIs) are antibodies that target key signalling pathways
such as programmed death 1 (PD1)/programmed death-ligands 1 and 2 (PDL1 and PDL2) to …