… evolving field, with a focus on immune checkpoint inhibitors as a potential treatment approach
for a variety of cancers… of dual T-cell checkpoint inhibition with ipilimumab and nivolumab …

… checkpoints have been identified and are emerging as successful and promising targets in
cancer … Here, we highlight traditional immune checkpoint inhibitors (ICIs) that are already in …

… checkpoint inhibitors (CPIs) are rapidly becoming standard of care for many cancers. Here,
… the influence of ITH on patient response to immune checkpoint inhibitor (CPI) therapy. At its …

… fight against cancers. However, … checkpoint inhibitors or co-stimulatory activators, and
possibly combining with conventional oncological therapies. Some of the new checkpoint inhibitors…

… Currently approved immune checkpoint inhibitors (ICIs) target core inhibitory pathways (CTLA4
and PD(L)1) that sit atop of an intricate network of opposing signals, evolved to avoid …

… Overview of immune pathways and actions of checkpoint inhibitors. The role of immune
checkpoint inhibitors in restoring antitumor activity. Immune checkpoint proteins are expressed …

… Checkpoint inhibitor-based immunotherapies that target … success in the treatment of different
cancer types. Yet, only a … work demonstrating that immune checkpoint inhibitor efficacy is …

… checkpoint inhibitors and discusses the scientific overview of cancer immunotherapy,
mechanisms of the inhibitors, … relatively early in the evolution of cancer drugs and became the …

… , with modest response to checkpoint inhibitor monotherapy. In … with checkpoint inhibitors as
the linchpins of cancer treatment. … mutation, adaptive evolution within cancer generally limits …

… Furthermore, depending on clinical responses in diverse cancer types, checkpoint inhibitors…
of many cancer patients. These treatments have revolutionized cancer immunotherapy by …