… in chemical biology research driven by organic chemistry, with a focus on bioorthogonal …
organic chemistry in chemical biology research: linker systems that allow mild cleavage under …

… cleavable linker. Since then, numerous advances in the development of ACPPs and their
triggers have been reported. In this review, we provide an overview of the strategies in the …

… cleavable ortho-nitrobenzyl linkers and PNAs to perform templated NCL with short model
peptides [65]. The Okamoto lab used a similar UV-cleavable linker … of complex linker syntheses …

… In conclusion, ACT-based probes with Dde cleavable linker offer several key features: (1) …
sites, and (3) applicability to native biological systems like mouse brain slices. We believe that …

… Attaching a cathepsin B-cleavable linker to the 600-modified α-GalCer created pro-adjuvants
bearing a pendant ketone group available for peptide conjugation. Optimized reaction …

… Stability of the drug-linker in circulation is important because … Directly linked ADCs and
protease-cleavable linkers are … two linkers can be tuned by altering the neighboring chemical …

… organometallic chemistry” [16] and “bioorganometallic chemistry” [17]… the interface of
organometallic chemistry and chemical biology, which … (c) Chemical decaging for cleavable …

… In addition to a terminal alkyne for capture of azide-containing saccharides, we wanted to
introduce a cleavage site in the linker to facilitate the analysis of the covalent array by standard …

… With the advantages of modular synthesis and stimuli-responsive drug release, we
believe Val-Ala(NB) will be a potentially valuable cleavable linker for use in oligonucleotide-drug …

… PD-strained alkyne 1 as our choice of linker in this study. The … ADC bearing an extracellular
cleavable linker could display anti-… , we chose a linker-payload combination consisting of the …