… a mixture of chemicals with simple similar action. Safety evaluation of complex chemical
mixtures is a challenge … the (eg ten) most risky chemicals in the mixture, and, second, assess the …

… to chemical mixtures is a daunting challenge to many … chemical mixtures during the past
15 years, reviews today's state of the art of mixture toxicology, and discusses future challenges …

… Today, DDT has been replaced in many countries with agents such as pyrethroids. …
Methylmercury and the health of indigenous peoples: a risk management challenge for physical and …

… Today, awareness is … challenges in developing chemical regulations and infrastructure such
as wastewater treatment (2). Awareness of the need to deal with complex chemical mixtures …

… today, including pharmacology, pesticide toxicology, occupational toxicology, and environmental
toxicology. The toxicology we practice today was … , the challenge of chemical mixtures is …

… the development of approaches that, as we hope, will finally lead to an integration of
chemical with systems-level biological information for predicting the effect of chemical mixtures. …

… (5) report that some 80,000 chemicals are in use today, that nearly 10% are recognized as
… the cellular and molecular levels present enormous challenges to toxicologists. A number of …

… In the world we live in today, it is virtually impossible for a person to live in an environment
that is toxicant-free. Our challenge in trying to evaluate the impact of xenobiotics is to try to …

… of mixtures more critical and challenging. Interactions of individual chemicals in a mixture can
result in … Until today most of the computational approaches have been employed for single …

… Given the magnitude of the challenge of mixture toxicity, it is clear that substantial … the fate
of the components of chemical mixtures in organisms and extrapolating experimental results …