[HTML][HTML] Regulatory assessment of chemical mixtures: requirements, current approaches and future perspectives
A Kienzler, SK Bopp, S van der Linden… - Regulatory Toxicology …, 2016 - Elsevier
… regulatory requirements for chemical mixture assessment, with … the assessment of intentional
and unintentional mixtures. … on mixture RA beyond the current regulatory requirements are …
and unintentional mixtures. … on mixture RA beyond the current regulatory requirements are …
Regulatory assessment and risk management of chemical mixtures: challenges and ways forward
SK Bopp, A Kienzler, AN Richarz… - Critical Reviews in …, 2019 - Taylor & Francis
… assessment of specific chemical mixtures, the option of taking account of possible mixture
effects in single substance risk assessments … impact on the assessment. Considering the large …
effects in single substance risk assessments … impact on the assessment. Considering the large …
Chemical mixtures: considering the evolution of toxicology and chemical assessment
E Monosson - Environmental health perspectives, 2005 - ehp.niehs.nih.gov
… -chemical database. It is also clear that b) the science and assessment of chemical mixtures
are moving forward through the combined efforts of regulatory agencies and scientists from …
are moving forward through the combined efforts of regulatory agencies and scientists from …
[HTML][HTML] Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment
E Drakvik, R Altenburger, Y Aoki, T Backhaus… - Environment …, 2020 - Elsevier
… Existing proposals for tiered regulatory approaches to mixture risk assessment largely
focus on component-based approaches (CBAs). These are scientifically reasonable but when …
focus on component-based approaches (CBAs). These are scientifically reasonable but when …
Review of the toxicity of chemical mixtures: theory, policy, and regulatory practice
LS McCarty, CJ Borgert - Regulatory Toxicology and Pharmacology, 2006 - Elsevier
… Toxicity information could be classed into several approaches for use in risk assessment
of chemical mixtures. The toxicity equivalency factor (TEF) approach, as employed for …
of chemical mixtures. The toxicity equivalency factor (TEF) approach, as employed for …
[PDF][PDF] Assessment of mixtures-review of regulatory requirements and guidance
A Kienzler, E Berggren, J Bessems… - JRC Science for …, 2014 - researchgate.net
… are used to assess the toxic effects of mixtures. It … assessment of chemicals in different
matrices and the extent to which the current legislation addresses the toxicological risk of mixtures. …
matrices and the extent to which the current legislation addresses the toxicological risk of mixtures. …
Low dose mixture effects of endocrine disrupters and their implications for regulatory thresholds in chemical risk assessment
A Kortenkamp - Current opinion in pharmacology, 2014 - Elsevier
… A dilemma for chemical risk assessment: the numbers game Whichever way we look at
the low dose mixture issue, it exposes an assessment dilemma. According to dose addition, …
the low dose mixture issue, it exposes an assessment dilemma. According to dose addition, …
Environmental risk assessment of technical mixtures under the European registration, evaluation, authorisation and restriction of chemicals—a regulatory perspective
W Galert, E Hassold - Integrated Environmental Assessment …, 2021 - Wiley Online Library
… Starting points could be voluntary action or product responsibility for a mixture assessment.
We see a discrimination in the assessment of technical mixtures in contrast to substances in …
We see a discrimination in the assessment of technical mixtures in contrast to substances in …
[HTML][HTML] Should the scope of human mixture risk assessment span legislative/regulatory silos for chemicals?
RM Evans, OV Martin, M Faust… - Science of the Total …, 2016 - Elsevier
… risk assessment (MRA). Whilst there is a broad consensus on the basic science of mixture
toxicology, the path to regulatory implementation of MRA within chemical risk assessment is …
toxicology, the path to regulatory implementation of MRA within chemical risk assessment is …
Evaluating chemical mixtures in epidemiological studies to inform regulatory decisions
DA Savitz, AM Hattersley - Environmental health perspectives, 2023 - ehp.niehs.nih.gov
… At its most basic level, we define a chemical mixture as simply a set of individual chemicals
that have been designated as a combined entity for some purpose, eg, for assessing health …
that have been designated as a combined entity for some purpose, eg, for assessing health …
相关搜索
- toxicology of chemical mixtures
- risk assessment of chemical mixtures
- chemical mixtures epidemiological studies
- chemical mixtures human health
- chemical mixtures health effects
- regulatory practice toxicity of chemical mixtures
- chemical mixtures public health practice
- chemical mixtures unsolvable riddle
- challenges and ways regulatory assessment
- chemical mixtures status and ways
- chemical mixtures informed decision making
- chemical mixtures regulatory decisions
- chemical mixtures challenges for today
- chemical mixtures separate lines
- chemical mixtures challenging quest
- chemical mixtures empirical sciences