Deciding which chemical mixtures risk assessment methods work best for what mixtures

LK Teuschler - Toxicology and Applied Pharmacology, 2007 - Elsevier
… for conducting a chemical mixtures risk assessment: (1) … of mixture components; (2)
toxicological interactions of mixture components; and (3) chemical composition of complex mixtures. …

Predictive environmental risk assessment of chemical mixtures: a conceptual framework

T Backhaus, M Faust - Environmental science & technology, 2012 - ACS Publications
… conditions to real life and from single substance data to chemical mixtures we suggest a
two-tiered approach for predictive environmental risk assessment of mixtures (Figure 2). …

Regulatory assessment and risk management of chemical mixtures: challenges and ways forward

SK Bopp, A Kienzler, AN Richarz… - Critical Reviews in …, 2019 - Taylor & Francis
assessment of specific chemical mixtures, the option of taking account of possible mixture
effects in single substance risk assessments … in mixture risk assessment (MRA) but also the risk

Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach.

SH Safe - Environmental health perspectives, 1998 - ehp.niehs.nih.gov
chemical interactions are important determinants in evaluating the potential hazards and risks
of exposure to chemical mixtures… (TEF) approach for risk assessment of complex mixtures. …

Toxicological evaluation and risk assessment of chemical mixtures

FR Cassee, JP Groten, PJ Bladeren… - Critical Reviews in …, 1998 - Taylor & Francis
… of chemical mixtures and to assess their potential health risks it is essential to be familiar
with the basic concepts of combined action and interaction of chemicals in a mixture and to …

New approaches to risk assessment of chemical mixtures

AW Hayes, R Li, J Hoeng, A Iskandar… - Toxicology …, 2019 - journals.sagepub.com
mixture-based and component-based evaluations. Emerging technologies have enabled rapid
mixture … the approaches to risk assessment of complex chemical mixtures as presented at …

Current and future risk assessment guidelines, policy, and methods development for chemical mixtures

LK Teuschler, RC Hertzberg - Toxicology, 1995 - Elsevier
risk assessment procedures. The US EPA developed guidelines for risk assessment for
chemical mixtures in … or that represent future directions in chemical mixtures risk assessment. …

Chemical mixtures: current risk assessment methodologies and future directions

J Seed, RP Brown, SS Olin, JA Foran - Regulatory Toxicology and …, 1995 - Elsevier
… for risk assessment of chemical mixtures. This paper reviews the existing and newly developed
risk assessment methodologies for mixtures … exposure to chemical mixture components. …

[HTML][HTML] Statement on advancing the assessment of chemical mixtures and their risks for human health and the environment

E Drakvik, R Altenburger, Y Aoki, T Backhaus… - Environment …, 2020 - Elsevier
… This forum for researchers and policy-makers was created to discuss and identify gaps in
risk assessment and governance of chemical mixtures as well as to discuss state of the art …

A pragmatic approach for human risk assessment of chemical mixtures

J Boberg, M Dybdahl, A Petersen, U Hass… - Current Opinion in …, 2019 - Elsevier
… procedure for mixture risk assessment and propose tools for grouping of chemicals. Until we
… , we suggest that grouping of chemicals for mixture risk assessment be based on integrated …