… of structural organic chemistry. At the outset we distinguish between self-replication and other
… of these model systems to prebiotic chemistry or biology. As our experiments hinged on a …

… This autocatalysis typically takes the form of replication templated by specific non-covalent …
focus on self-replicating systems comprising completely synthetic molecules as well as bio-…

… idea of self-synthesising and self-repairing chemical factories. … obtaining adaptive, self-healing,
self-replicating and ultimately … In biology, many important self-assembly processes are …

… The theory of Darwinian evolution describes the origin of biological information. In
general, … chemists to trace back the original path of evolution by “reinventing” simple self-replicating …

… Recent advances in the area of self-replication have led to … of replication, and by
improving the efficiency of the catalysts themselves. This review analyzes chemical self-replicating …

… extant or plausible primordial biological systems, as nucleic acids are uniquely suited for
self-replication, heredity, and evolution. We also briefly discuss chemical replicators based on …

… While the hallmark of biology is the ability to self-replicate, this ability is found only rarely
outside of cells. Cell-based organisms have an almost unique claim on the ability to …

… of life: Life is a self-sustained chemical system capable of undergoing Darwinian evolution.
… in our understanding of biological processes, such as DNA replication, protein synthesis, …

… the critical frontier between organic chemistry and biology. In 1953 Stanley L. Miller… self-replication.
Molecules, natural or synthetic, are able to replicate when their shapes and chemistry …

… between systems chemistry23 and evolutionary biology. The … reversible covalent chemistry
combine and recombine to give … library to an irreversible self-replication process30–36 can …