Gemcitabine loaded microbubbles for targeted chemo-sonodynamic therapy of pancreatic cancer

H Nesbitt, Y Sheng, S Kamila, K Logan… - Journal of controlled …, 2018 - Elsevier
… suggest that chemo-sonodynamic therapy using the O 2 MB-Gem and O 2 MB-RB
conjugates, is potentially an effective targeted and safe treatment modality for pancreatic cancer. …

Combining sonodynamic therapy with chemoradiation for the treatment of pancreatic cancer

RJ Browning, S Able, JL Ruan, L Bau, PD Allen… - Journal of Controlled …, 2021 - Elsevier
… Therefore, in addition to the beneficial therapeutic effect of combining SDT and antimetabolite
chemotherapy, we hypothesise that SDT may also compliment chemoradiotherapy. As …

Hypoxia-alleviated nanoplatform to enhance chemosensitivity and sonodynamic effect in pancreatic cancer

J Chen, Y Bao, Y Song, C Zhang, F Qiu, Y Sun, L Xin… - Cancer Letters, 2021 - Elsevier
… the sensitivity of cancer cells to chemotherapy. Further, under … oxygen for the augmented
sonodynamic effect. Therefore, this … for chemo-sonodynamic therapy against pancreatic cancer. …

Hypoxia-adapted sono-chemodynamic treatment of orthotopic pancreatic carcinoma using copper metal–organic frameworks loaded with an ultrasound-induced free …

Y Sun, J Cao, X Wang, C Zhang, J Luo… - … Applied Materials & …, 2021 - ACS Publications
… The efficacy of sonodynamic therapy (SDT) is largely … to improve the efficacy of sonodynamic
antitumor therapy. As … the antitumor performance of this chemo-sonosensitizer. Subsequent …

Oxygen-self-produced nanoplatform for relieving hypoxia and breaking resistance to sonodynamic treatment of pancreatic cancer

J Chen, H Luo, Y Liu, W Zhang, H Li, T Luo, K Zhang… - ACS …, 2017 - ACS Publications
… , an oxygen-self-produced sonodynamic therapy (SDT) … highly efficient SDT against hypoxic
pancreatic cancer. In this … shrink hypoxic PANC-1 pancreatic cancer. This distinctive FC-…

Tablet-like TiO2/C nanocomposites for repeated type I sonodynamic therapy of pancreatic cancer

J Cao, Y Sun, C Zhang, X Wang, Y Zeng, T Zhang… - Acta Biomaterialia, 2021 - Elsevier
… I sonodynamic therapy of hypoxic pancreatic tumor. … Pancreatic cancer is a highly prevalent
and deadly cancer type, with the 5-year survival of those with metastatic pancreatic cancer

Oxygen-carrying microfluidic microcapsules for enhancing chemo-sonodynamic therapy on patient-derived tumor organoid models

D Huang, C Zhao, B Wen, X Fu, L Shang… - Chemical Engineering …, 2022 - Elsevier
… of chemo-sonodynamic therapy against pancreatic cancer. It is … -tumor effect in patient-derived
pancreatic cancer organoid … enhancing chemo-sonodynamic therapy for hypoxic tumors. …

Recent advances in sonodynamic therapy strategies for pancreatic cancer

P Cheng, S Ming, W Cao, J Wu, Q Tian… - Wiley …, 2024 - Wiley Online Library
… The application of UTMD, a more efficient method of delivering the chemotherapy … significantly
diminishes the overall chemotherapy burden, particularly for pancreatic cancer (Figure 7). …

Corrole nanoparticles for chemotherapy of castration-resistant prostate cancer and as sonodynamic agents for pancreatic cancer treatment

M Soll, VK Sharma, S Khoury… - Journal of Medicinal …, 2022 - ACS Publications
… Also demonstrated is the potential application of these 3-Ga NPs as sonodynamic agents
for the preclinical treatment of pancreatic cancer. 10 mg/kg 3-Ga NPs combined with exposure …

Sonodynamic therapy complements PD-L1 immune checkpoint inhibition in a murine model of pancreatic cancer

H Nesbitt, K Logan, K Thomas, B Callan, J Gao… - Cancer Letters, 2021 - Elsevier
… systemic side effects making it better tolerated than other cancer treatments such as
chemotherapy and radiotherapy. The efficacy of SDT has been demonstrated in a range of different …