[HTML][HTML] Alterations in brain neurocircuitry following treatment with the chemotherapeutic agent paclitaxel in rats

CF Ferris, S Nodine, T Pottala, X Cai, TM Knox… - Neurobiology of Pain, 2019 - Elsevier
… challenge with chemotherapeutic agents involves the reorganization of neural circuits in the
brain. … (MRI) to identify changes in brain neural circuitry that accompany the development of …

Neuropathological effects of chemotherapeutic drugs

A Umfress, HE Speed, C Tan, S Ramezani… - ACS chemical …, 2021 - ACS Publications
… This study contributes to growing evidence of the deleterious effects that chemotherapy
can have on brain function and warrants further studies investigating the mechanisms behind …

Mechanisms of chemotherapy-induced neurotoxicity

H Was, A Borkowska, A Bagues, L Tu… - Frontiers in …, 2022 - frontiersin.org
… Below, we describe the involvement of the different chemotherapeutic drugs and various …
the level of chemotherapeutics in the brain. The presence of those polymorphisms allows toxic …

Review of the role of the brain in chemotherapy-induced peripheral neuropathy

M Omran, EK Belcher, NA Mohile, SR Kesler… - Frontiers in Molecular …, 2021 - frontiersin.org
… responses in the brain that contribute to CIPN even if chemotherapy drugs do not enter
the brain, as we discuss below. We postulate that knowledge of both peripheral and brain-based …

Neurotoxic effects of anthracycline-vs nonanthracycline-based chemotherapy on cognition in breast cancer survivors

SR Kesler, DW Blayney - JAMA oncology, 2016 - jamanetwork.com
brain against the effects of various chemotherapeutic agents. … by which ANTHRs disrupt
neurocircuitry could help identify … ANTHR agents are able to penetrate the blood-brain barrier …

[HTML][HTML] Neuroimaging uncovers neuronal and metabolic changes in pain modulatory brain areas in a rat model of chemotherapy-induced neuropathy–MEMRI and ex …

JT Costa-Pereira, R Oliveira, I Guadilla, MJ Guillén… - Brain Research …, 2023 - Elsevier
Chemotherapeutics agents are the drugs most employed in cancer treatment.
Chemotherapy-induced neuropathy (CIN) is a frequent complication during cancer treatment, and it …

Centralizing the Knowledge and Interpretation of Pain in Chemotherapy-Induced Peripheral Neuropathy: A Paradigm Shift towards Brain-Centric Approaches

M Cunha, I Tavares, JT Costa-Pereira - Brain Sciences, 2024 - mdpi.com
… , S.; Kulkarni, P.; Crystal, JD; Hohmann, AG Alterations in brain neurocircuitry following
treatment with the chemotherapeutic agent paclitaxel in rats. Neurobiol. Pain 2019, 6, 100034. …

New approaches to chemotherapy-induced nausea and vomiting: from neuropharmacology to clinical investigations

EB Rubenstein, BS Slusher, C Rojas… - The Cancer …, 2006 - journals.lww.com
Chemotherapeutic agents are toxic to the enterochromaffin cells lining the upper … brain;
compounds that agonize GABA receptors are used clinically as antiepileptic and sedation agents

Impaired brain dopamine transporter in chemobrain patients submitted to brain SPECT imaging using the technetium-99m labeled tracer TRODAT-1

T Vitor, EH Kozasa, RA Bressan, SS Lacerda… - Annals of Nuclear …, 2019 - Springer
chemotherapeutic agents may impair neurotransmitter signaling [10]. Both dividing and
nondividing progenitor cells and oligodendrocytes in the brain … as other neurocircuits such as …

Centralizing the knowledge and interpretation of pain in Chemotherapy-Induced Peripheral Neuropathy: a paradigm shift towards brain-centric approaches

MMC de Vasconcelos Campos - 2024 - repositorio-aberto.up.pt
chemotherapeutic agent on the brain during the progression of polyneuropathy, at several
… in brain neurocircuitry following treatment with the chemotherapeufic agent paclitaxel in rats. …