Resistance to multiple chemotherapeutic agents in human cancer cells

MM Gottesman, I Pastan - Trends in pharmacological sciences, 1988 - cell.com
Human cancer cells selected for resistance to multiple hydrophobic cytotoxic drugs express
the cell surface P-glycoprotein, which is the product of the MDRl gene. In this review Michael …

Chemotherapeutic agents in low noncytotoxic concentrations increase immunogenicity of human colon cancer cells

R Kaneno, GV Shurin, FM Kaneno, H Naiditch, J Luo… - Cellular oncology, 2011 - Springer
… concentrations of chemotherapeutic agents, a … tumor cell-based and DC-based vaccines.
Our results also suggest a new mechanism of how a very low dose of chemotherapeutic agents

[HTML][HTML] Diversity of the senescence phenotype of cancer cells treated with chemotherapeutic agents

A Bojko, J Czarnecka-Herok, A Charzynska… - Cells, 2019 - mdpi.com
… of several cancer cell lines treated with different anticancer drugs using a set of common
senescence markers. Our results point to a cell type and drug diversity in the cancer cell

Optimal delivery of chemotherapeutic agents in cancer

P Dua, V Dua, EN Pistikopoulos - Computers & Chemical Engineering, 2008 - Elsevier
… to the normal cells. In this paper, two models for cancer chemotherapy are considered and
the … The first model considers the case when the chemotherapeutic agents kill cancer cells

The effectiveness of various chemotherapeutic agents in cancer treatment

J Kashifa Fathima, V Lavanya, S Jamal… - Current Pharmacology …, 2022 - Springer
… Though chemotherapeutic agents have effect on cancer cells, their usage … chemotherapeutic
agents in less dosage with higher dosage of polyphenols are less cytotoxic to normal cells. …

[HTML][HTML] Tyrosine kinase inhibitors enhanced the efficacy of conventional chemotherapeutic agent in multidrug resistant cancer cells

S Wu, L Fu - Molecular cancer, 2018 - Springer
… of the main reasons for chemotherapy failure, leading to the … chemotherapeutic drug out
of cancer cells, decrease intracellular accumulation of anticancer drug and result in cancer cell

Enhanced in vitro selective toxicity of chemotherapeutic agents for human cancer cells based on a metabolic defect

PH Stern, RM Hoffman - JNCI: Journal of the National Cancer …, 1986 - academic.oup.com
… of administering chemotherapy on the basis of metabolic differences between normal and
cancer cells. Perhaps this approach will finally lead to effective chemotherapy for many types …

Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells

B Agarwal, S Bhendwal, B Halmos, SF Moss… - Clinical Cancer …, 1999 - AACR
… for cancers. We therefore studied whether combinations of the HRI lovastatin with standard
chemotherapeutic agents would augment apoptosis in colon cancer cells. In the colon …

Advances in delivery of chemotherapeutic agents for cancer treatment

A Yadav, S Singh, H Sohi, S Dang - AAPS PharmSciTech, 2022 - Springer
… is the preferred choice in case of metastatic cancers [2]. Chemotherapy leads to the suppression
of cell division which is a characteristic feature of cancer cells. However, rapidly dividing …

PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation

J Yu, W Yue, B Wu, L Zhang - Clinical cancer research, 2006 - AACR
… of PUMA by chemotherapeutic agents is abolished in p53-deficient lung cancer cells.
PUMA expression resulted in potent growth suppression of lung cancer cells and suppressed …