Optimal delivery of chemotherapeutic agents in cancer

P Dua, V Dua, EN Pistikopoulos - Computers & Chemical Engineering, 2008 - Elsevier
… and optimization approaches can be employed to obtain effective chemotherapeutic protocol
… In this paper, two models for cancer chemotherapy are considered and the effect of the time …

Advances in delivery of chemotherapeutic agents for cancer treatment

A Yadav, S Singh, H Sohi, S Dang - AAPS PharmSciTech, 2022 - Springer
chemotherapeutic drug delivery systems are claiming to enhance the bioavailability and drug
solubility, augment the biodistribution of chemotherapeutic agents, … best supportive care vs. …

Finding the optimal balance: challenges of improving conventional cancer chemotherapy using suitable combinations with nano-sized drug delivery systems

F Kratz, A Warnecke - Journal of controlled release, 2012 - Elsevier
… strategies of conventional chemotherapy with nano-sized drug delivery systems are … cancer
with drug delivery systems alone but rather whether we will make further progress in cancer

Optimization of drug delivery systems for intraperitoneal therapy to extend the residence time of the chemotherapeutic agent

L De Smet, W Ceelen, JP Remon… - The Scientific World …, 2013 - Wiley Online Library
delivery and extend the residence time of the cytotoxic agent in the peritoneal cavity. This
paper reviews the recent advances made in drug delivery systems for IP chemotherapydelivery

Nanoparticle-mediated co-delivery of chemotherapeutic agent and siRNA for combination cancer therapy

B Xiao, L Ma, D Merlin - Expert opinion on drug delivery, 2017 - Taylor & Francis
… used as delivery systems for individual chemotherapeutic agent or … for the co-delivery of
chemotherapeutic agents and siRNAs owing … Ideal NPs for co-delivery of drugs should have the …

Advanced engineered nanoparticulate platforms to address key biological barriers for delivering chemotherapeutic agents to target sites

J Cao, D Huang, NA Peppas - Advanced Drug Delivery Reviews, 2020 - Elsevier
… achieved to date and several nanoscale delivery systems for the chemotherapy drugs
paclitaxel (PTX) or doxorubicin (DOX) have been approved for treating cancer in clinic, the clinical …

Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors

DC Drummond, O Meyer, K Hong, DB Kirpotin… - Pharmacological …, 1999 - ASPET
There are many potential barriers to the effective delivery of a drug in its active form to solid
tumors. Most small-molecule chemotherapeutic agents have a large volume of distribution on …

Optimal delivery of cytotoxic chemotherapy for colon cancer

L Raftery, RM Goldberg - The Cancer Journal, 2010 - journals.lww.com
optimal sequence of delivery of chemotherapy for CRC. The Sequential Versus Combination
Chemotherapy … the proportion of patients receiving all 3 cytotoxic chemotherapeutic agents. …

Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

E Pérez-Herrero, A Fernández-Medarde - European journal of …, 2015 - Elsevier
… or specific cancer proteins to induce the death of cancer cells … specifically deliver
chemotherapeutic agents to cancer cells, … that mainly deliver chemotherapeutic agents to …

[图书][B] Optimal control of drug administration in cancer chemotherapy

R Martin, KL Teo - 1994 - books.google.com
… control problem, and the control may represent the rate of delivery of the drug (Chapter 7) or
… modelled in the current study are assumed to be cycle-non-specific (eg alkylating agents), …