Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances
… adopted for the delivery of siRNA/miRNA combinations with other anticancer agents (…
with siRNA or miRNA significantly enhances the sensitivity of chemotherapeutic drugs by …
with siRNA or miRNA significantly enhances the sensitivity of chemotherapeutic drugs by …
[HTML][HTML] The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer
… In this post-genomic era, microRNAs (miRNAs) are receiving … of miRNAs and chemotherapeutic
agents for cancer treatment. Moreover, we attempted to portray the role of miRNAs in …
agents for cancer treatment. Moreover, we attempted to portray the role of miRNAs in …
Nanoparticle-mediated co-delivery of chemotherapeutic agent and siRNA for combination cancer therapy
… of chemotherapy and RNAi technology holds great promise as a new strategy for cancer
treatment. However, the chemotherapeutic agents and siRNAs … rather than miRNA and piRNA […
treatment. However, the chemotherapeutic agents and siRNAs … rather than miRNA and piRNA […
Nanocarrier-based co-delivery of small molecules and siRNA/miRNA for treatment of cancer
… chemotherapeutic agent could be delivered along with oligonucleotide/s (siRNA/miRNA)
to … Thus gene-based therapeutics in combination with potent chemotherapeutic agents is a …
to … Thus gene-based therapeutics in combination with potent chemotherapeutic agents is a …
Encapsulation of miRNA and siRNA into Nanomaterials for Cancer Therapeutics
… using siRNA, and hence the design of novel drugs, ie, cancer drugs in combination with
siRNA, … Nanoparticle platforms incorporating miRNA and chemotherapeutic drugs have been …
siRNA, … Nanoparticle platforms incorporating miRNA and chemotherapeutic drugs have been …
A double-modulation strategy in cancer treatment with a chemotherapeutic agent and siRNA
K Nakamura, ASA Lila, M Matsunaga, Y Doi, T Ishida… - Molecular Therapy, 2011 - cell.com
… , in which chemotherapy enhances intratumoral siRNA delivery and the delivered siRNA …
Combination of siRNA-containing nanocarriers with chemotherapy may compensate for the …
Combination of siRNA-containing nanocarriers with chemotherapy may compensate for the …
[HTML][HTML] New paradigm in combination therapy of siRNA with chemotherapeutic drugs for effective cancer therapy
… miRNA (Micro RNA) miRNAs are single-stranded, non-coding RNA oligonucleotides (20–25
base pairs). Multiple siRNAs can be created from a single miRNA transcript. They target …
base pairs). Multiple siRNAs can be created from a single miRNA transcript. They target …
[HTML][HTML] Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators
M Geretto, A Pulliero, C Rosano… - American journal of …, 2017 - ncbi.nlm.nih.gov
… Dicer in complex with different siRNA were solved [124]. A visual analysis of these structures
confirmed that the 2 nucleotide overhangs at the 3’ end of the siRNA are located in the PAZ …
confirmed that the 2 nucleotide overhangs at the 3’ end of the siRNA are located in the PAZ …
[HTML][HTML] Nanocarrier-mediated co-delivery of chemotherapeutic drugs and gene agents for cancer treatment
L Kang, Z Gao, W Huang, M Jin, Q Wang - Acta Pharmaceutica Sinica B, 2015 - Elsevier
… siRNA and miRNA can selectively knock down the carcinogenic genes by targeting specific
mRNAs. Therefore, combining chemotherapeutic drugs with gene agents … agents and drugs, …
mRNAs. Therefore, combining chemotherapeutic drugs with gene agents … agents and drugs, …
Employing siRNA tool and its delivery platforms in suppressing cisplatin resistance: approaching to a new era of cancer chemotherapy
… of siRNA in suppressing cisplatin (CP) resistance in cancer. CP is a well-known chemotherapeutic
agent… factors including p15, p21, p27 and miRNA-218, while it reduces expressions of …
agent… factors including p15, p21, p27 and miRNA-218, while it reduces expressions of …
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