Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors

L Galluzzi, J Humeau, A Buqué, L Zitvogel… - Nature reviews Clinical …, 2020 - nature.com
… mechanisms that underlie the efficacy of chemotherapy has the potential not only to enable
… that enhance the clinical effectiveness of immune checkpoint inhibitors (ICIs) relative to their …

Immune-checkpoint inhibitor plus chemotherapy versus conventional chemotherapy for first-line treatment in advanced non-small cell lung carcinoma: a systematic …

Y Zhou, C Chen, X Zhang, S Fu, C Xue, Y Ma… - … for immunotherapy of …, 2018 - Springer
… Yet, this meta-analysis established the definite benefit of IO-chemotherapy vs chemotherapy
in terms of PFS and ORR in the first line setting, which might serve as moderate surrogate …

Combining immune checkpoint inhibitors with chemotherapy in advanced solid tumours: A review

M Larroquette, C Domblides, F Lefort… - European Journal of …, 2021 - Elsevier
… by the arrival of immune checkpoint inhibitors (ICIs), especially … as lymphocyte activation
gene 3 inhibitors, or could target various … The mechanism of action of standard chemotherapy is …

Immune checkpoint inhibitors and chemotherapy in first-line NSCLC: a meta-analysis

F Petrelli, R Ferrara, D Signorelli, A Ghidini… - …, 2021 - Taylor & Francis
… Only programmed death ligand-1 positive-high cancers derive a significant OS benefit. In …
checkpoint inhibitors to chemotherapy may improve both OS compared with chemotherapy

Immune checkpoint inhibitors, alone or in combination with chemotherapy, as first-line treatment for advanced non-small cell lung cancer. A systematic review and …

U Dafni, Z Tsourti, K Vervita, S Peters - Lung cancer, 2019 - Elsevier
… -checkpoint inhibitor (ICI) with or without chemotherapy, as … from randomized studies with
chemotherapy as the common … , the combination of chemotherapy, first with pembrolizumab, …

Combination of immune checkpoint inhibitors with chemotherapy in lung cancer

W Liu, L Zhang, Z Xiu, J Guo, L Wang… - OncoTargets and …, 2020 - Taylor & Francis
… Tremendous progress has been achieved in the field of immune checkpoint inhibitors (…
chemotherapy was considered as immunosuppressive. It is now recognized that chemotherapy

[HTML][HTML] First-line immune-checkpoint inhibitor combination therapy for chemotherapy-eligible patients with metastatic urothelial carcinoma: A systematic review and …

K Mori, B Pradere, M Moschini, H Mostafaei… - European Journal of …, 2021 - Elsevier
… these developments of immune-checkpoint inhibitors (ICIs), … or standard chemotherapy, for
platinum-based chemotherapy (… -on to platinum-based chemotherapy as a first-line treatment …

[HTML][HTML] Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors

KM Heinhuis, W Ros, M Kok, N Steeghs, JH Beijnen… - Annals of …, 2019 - Elsevier
chemotherapeutic agents on the immune system and the potential value of these different
types of chemotherapy as … groups of chemotherapy: topoisomerase inhibitors, antimicrotubule …

Molecular basis and rationale for combining immune checkpoint inhibitors with chemotherapy in non-small cell lung cancer

A Leonetti, B Wever, G Mazzaschi, YG Assaraf… - Drug Resistance …, 2019 - Elsevier
… of immune checkpoint inhibitors with chemotherapycheckpoint inhibitors pembrolizumab
and atezolizumab have already been approved by the FDA in combination with chemotherapy

[HTML][HTML] Immune-checkpoint inhibitors plus chemotherapy versus chemotherapy as first-line treatment for patients with extensive-stage small cell lung cancer

F Zhou, W Zhao, X Gong, S Ren, C Su… - … for ImmunoTherapy of …, 2020 - ncbi.nlm.nih.gov
… of immune-checkpoint inhibitors (ICIs) plus chemotherapy in patients … inhibitor plus
chemotherapy, 308 receiving PD-1 inhibitors plus chemotherapy, 563 receiving CTLA-4 inhibitors