Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer

A Satoh, M Toyota, F Itoh, Y Sasaki, H Suzuki, K Ogi… - Cancer research, 2003 - AACR
… checkpoint genes in a panel of gastric cancer cell lines and primary gastric cancer specimens.
… In summary, our data show that CHFR gene expression is frequently silenced by DNA …

[HTML][HTML] CHFR promoter hypermethylation is associated with gastric cancer and plays a protective role in gastric cancer process

D Dai, B Zhou, W Xu, H Jin, X Wang - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
… Several studies suggested that CHFR gene expression is … CHFR methylation and gastric
cancer. The results showed that the CHFR methylation was significantly higher in gastric cancer

[HTML][HTML] Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma

YJ Gao, Y Xin, JJ Zhang, J Zhou - World Journal of …, 2008 - ncbi.nlm.nih.gov
… status of the CHFR gene (P = 0.006). In 20 samples of corresponding non-neoplastic
mucosa, no DNA methylation of the CHFR gene was detected. The CHFR gene methylation in …

Association between CHFR gene hypermethylation and gastric cancer risk: a meta-analysis

H Shi, X Wang, J Wang, J Pan, J Liu… - OncoTargets and …, 2016 - Taylor & Francis
… The association between the hypermethylation of CHFR gene and gastric cancer risk has …
studies to assess the association between CHFR methylation and the risk of gastric cancer. …

Predictive value of CHFR and MLH1 methylation in human gastric cancer

Y Li, Y Yang, Y Lu, JG Herman, MV Brock, P Zhao… - Gastric cancer, 2015 - Springer
… markers in gastric cancer, we analyzed five DNA damage repair genes in this study. … In
conclusion, CHFR is frequently methylated in human gastric cancer, and CHFR meth ylation may …

[PDF][PDF] Promoter methylation of CHFR gene in gastric carcinoma tissues detected using two methods

ZD Cheng, SL Hu, YB Sun, WP Xu, G Shen… - … J Cancer, 2010 - scholar.archive.org
… In our study, we detected the methylation of CHFR gene in gastric cancer tissues using
both MSP and COBRA, colligated the advantages of the high sensitivity of MSP and high …

Pathobiologic implications of methylation and expression status of Runx3 and CHFR genes in gastric cancer

SL Hu, DB Huang, YB Sun, L Wu, WP Xu, S Yin… - Medical Oncology, 2011 - Springer
… of Runx3 and CHFR genes for primary gastric cancer tissues and corresponding normal
gastric mucosae. The methylation frequencies of Runx3 and CHFR in cancer tissues were …

Hypermethylation of Chfr and hMLH1 in gastric noninvasive and early invasive neoplasias

N Homma, G Tamura, T Honda, Z Jin, K Ohmura… - Virchows Archiv, 2005 - Springer
… of ten gastric cancer cell lines (20%) showed Chfr promoter … genes/mechanisms that lead
to CIN in gastric cancer. The association between Chfr methylation and LOH in other tumors

Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia

T Honda, G Tamura, T Waki, S Kawata… - … journal of cancer, 2004 - nature.com
… or tumour-related genes are not always cancer specific, the … genes (Waki et al, 2003a,
2003b). In the present study, we investigated Chfr promoter methylation status in gastric cancer

Aberrant methylation of the CHFR gene in digestive tract cancer

Y Morioka, K Hibi, M Sakai, M Koike… - Anticancer …, 2006 - ar.iiarjournals.org
… of the CHFR gene was examined in primary esophageal and gastric carcinomas. Materials
… In the present study, the methylation status and gene expression of CHFR in several cancer