Gene organisation determines evolution of function in the chicken MHC
… nucleolar organiser region (NOR), in which all ofthe chicken rRNA genes were located (18). …
based on the mammalian MHC, upon analysis of chicken MHC genes at the genomic level, …
based on the mammalian MHC, upon analysis of chicken MHC genes at the genomic level, …
Organisation and diversity of the class II DM region of the chicken MHC
O Chazara, M Tixier-Boichard, V Morin, R Zoorob… - Molecular …, 2011 - Elsevier
… -classical class II genes of the chicken. As shown … genes do exist in the B region of the MHC
of the chicken. And, in order to assess genetic diversity of these key immune system genes, …
of the chicken. And, in order to assess genetic diversity of these key immune system genes, …
Innate immune genes of the chicken MHC and related regions
J Kaufman - Immunogenetics, 2022 - Springer
… , the organisation of this MHC was arranged differently than in mammals, with the class III
region on the outside and the TAP genes in between the two class I genes, an organisation …
region on the outside and the TAP genes in between the two class I genes, an organisation …
Chickens as a simple system for scientific discovery: The example of the MHC
CA Tregaskes, J Kaufman - Molecular immunology, 2021 - Elsevier
… An example is the major histocompatibility complex (MHC) that encodes the classical MHC
… , the chicken MHC is compact and simple, with single dominantly-expressed MHC molecules …
… , the chicken MHC is compact and simple, with single dominantly-expressed MHC molecules …
Chicken TAP genes differ from their human orthologues in locus organisation, size, sequence features and polymorphism
… TAP promoter such as the interferon-response element, X/X2, Y and S boxes, which are
also found in the promoter regions of chicken MHC class I and β2-microglobulin promoters. In …
also found in the promoter regions of chicken MHC class I and β2-microglobulin promoters. In …
A potential nomenclature for the Immuno Polymorphism Database (IPD) of chicken MHC genes: progress and problems
… but organised with allele groups in the first field separated by a colon from closely related
variants in the second field, based on the system originally developed for human MHC genes …
variants in the second field, based on the system originally developed for human MHC genes …
The avian MHC
J Kaufman - Avian immunology, 2014 - Elsevier
… In other ways, the chicken MHC differs from the textbook … The chicken MHC has two class I
genes and two class II B genes, … If the chicken simply used all the genes, then a chicken MHC …
genes and two class II B genes, … If the chicken simply used all the genes, then a chicken MHC …
… “minimal essential MHC” revisited: both peptide‐binding and cell surface expression level of MHC molecules are polymorphisms selected by pathogens in chickens
J Kaufman, J Salomonsen - Hereditas, 1997 - Wiley Online Library
… This may mean that the organisation in chickens (and perhaps originally in the tetrapods)
was with the class I region in between the class I1 region and the class 111 region, rather than …
was with the class I region in between the class I1 region and the class 111 region, rather than …
What chickens might tell us about the MHC class II system
A Parker, J Kaufman - Current opinion in immunology, 2017 - Elsevier
… We have proposed that a genomic inversion within the ancestral organisation swung the
class III region into the middle of the MHC and the class I gene(s) to the outside, but leaving …
class III region into the middle of the MHC and the class I gene(s) to the outside, but leaving …
Characterisation of a cluster of TRIM-B30.2 genes in the chicken MHC B locus
T Ruby, B Bed'Hom, H Wittzell, V Morin, A Oudin… - Immunogenetics, 2005 - Springer
… Genomic organisation of the chicken MHC B complex. The map covers the BF/BL region (…
-like gene in the chicken MHC. Nevertheless, we here have shown that several BG genes are …
-like gene in the chicken MHC. Nevertheless, we here have shown that several BG genes are …
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