… Based on our direct observations, we conclude there is extensive variation in GC response
and isotype switching from IgM + to IgY + cells takes place in the presence of T cells. …

… B cell differentiation which occurs within the chicken spleen at defined time intervals after
immunization. Spleen cells … that the IgM cell line is unable to produce a T cell and macrophage-…

… , however existence of statistically higher IgG- and IgM-positive cells in the thymus of the
present study indicates that the B lymphocytes infiltrated in the thymus via blood circulation and …

… the sequence of appearance of cells actively secreting IgG, IgA, or IgM in young chicken …
of chicken spleen by Ig-secreting cells, as measured by the RHPA. IgM-secreting cells were …

… chickens, but their number decreases with aging (Jeurissen et al., 1988a). IgM, IgG, and lgA
plasma cells … postbursal stem cells are the only source of B-cell renewal in adult chickens, as …

… of spleen cells with anti-IgM-1 sera was heterogeneous and we could classify the sIgM-1
§ cells … up to a 1/320 dilution of anti-IgM-1 serum, whereas the more weakly stained cells ............ …

… -bound IgM, but also revealed some plasma cells with an … IgM-positive cells increased with
the age of the chicken. ChIgG-… or membrane-positive cells in the medulla of chickens 2 weeks …

… spleen, bursa and the B cell line RAV-1, but not from thymus or blood from an
agammaglobulinemic chicken… Our data indicate that chicken lymphocytes do indeed bear, in …

… T-cell marker, but did stain with anti-chicken IgM, an indicator for B … B cells leave the bursa
of Fabricius.27 This study has demonstrated that various compartments of the chicken spleen …

… IgG producing cells arise from the IgM clone of cells. IgA forming cells are derived from cells
… -BSA) only when spleen cells of bursectomized chickens (lacking B cells) sensitized to BSA …