… protein of Chlamydia trachomatis elementary bodies which corresponds to the polypeptide
(pgp3… Amino acid analysis showed that the first residue (Gly) found in the native protein is the …

… Chlamydia trachomatis infection is the most common sexually transmitted bacterial disease.
Left untreated, … Here we present the structure of the secreted C. trachomatis protein Pgp3, an …

… trachomatis infection in humans in the current … chlamydial proteins and evaluate chlamydial
protein immunogenicity in humans, we detected the recognition of chlamydial fusion proteins …

… whether the Pgp3 protein secreted by C. trachomatis could regulate the host oxidative stress
through activation Nrf2/NQO1 signal pathway. Our results indicated that Pgp3 induced Nrf2 …

… Chlamydia trachomatis plasmid-encoded Pgp3 protein is dependent on the native conformation
of Pgp3… The structural basis for the conformation dependence and the function of Pgp3 …

… Since Bcl-2 family members have been shown to play a pivotal role in chlamydial antiapoptotic
activity, we evaluated whether Pgp3 protein regulated the apoptosis-related proteins Bcl-…

… factor α-induced protein 3 (TNFAIP3) … chlamydial plasmid-encoded Pgp3 protein augmented
TNFAIP3 agrees with a previous report which infected HeLa cells using plasmid-bearing C…

… The protein featured in this work, pORF5, or Pgp3, is the only secreted plasmid-encoded
protein and it is distributed … Pgp3 is a key virulence factor in C. muridarum (a model for studying …

… In this work, we show that the C. trachomatis plasmid protein gene 3 (Pgp3) is the essential
… tract infection and provide supportive evidence that Pgp3 functions similarly in a nonhuman …

… As an obligate intracellular pathogen, Chlamydia trachomatis assumes various strategies to
… we revealed that Pgp3 protein, one of eight plasmid proteins of C. trachomatis that has been …