Cholesterol regulates the cell surface expression of glycophospholipid-anchored CD14 antigen on human monocytes

M Esfahani, RD Bigler, JL Alfieri, S Lund-Katz… - … et Biophysica Acta (BBA …, 1993 - Elsevier
… of cellular cholesterol depletion and repletion on cellcellular cholesterol. Immunofluorescence
analysis demonstrated a markedly diminished surface expression of CD14 on cells

Increased expression of CD14 in macrophages after inhibition of the cholesterol biosynthetic pathway by lovastatin

T Frey, A De Maio - Molecular medicine, 2007 - Springer
… The role of cholesterol depletion in altered CD14 expression … cellular cholesterol levels
between control and lovastatin treated macrophages. Small changes in the cellular cholesterol

Soluble CD14 mediates efflux of phospholipids from cells

T Sugiyama, SD Wright - The Journal of Immunology, 2001 - journals.aai.org
… and brought to the liver by a process known as “reverse cholesterol transport.” Additional
data also argue for net movement of phospholipids to HDL. Plasma contains several enzymes, …

Crosstalk between reverse cholesterol transport and innate immunity

KM Azzam, MB Fessler - Trends in Endocrinology & Metabolism, 2012 - cell.com
… to gut, referred to as ‘reverse cholesterol transport’ and how LPS … CD14 on cell membranes
or in plasma (sCD14). In addition to interactions with CD14/TLR4, LPS is taken up into cells

Identification of miR-9-5p as direct regulator of ABCA1 and HDL-driven reverse cholesterol transport in circulating CD14+ cells of patients with metabolic syndrome

S D'Amore, J Härdfeldt, M Cariello… - Cardiovascular …, 2018 - academic.oup.com
CD14 + cells of MS patients and are negatively correlated to body mass index (BMI),
insulin-resistance (HOMA-IR) and cardiovascular risk, and positively to HDL cholesterol … B cell (NF-…

Lipopolysaccharide-binding protein and soluble CD14 transfer lipopolysaccharide to phospholipid bilayers: preferential interaction with particular classes of lipid.

MM Wurfel, SD Wright - Journal of immunology (Baltimore, Md …, 1997 - journals.aai.org
… Our observation that LBP and sCD14 can transport LPS into phospholipid bilayers suggests
that LBP and membrane CD14 may transport LPS into the phospholipid bilayer of cells such …

Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation

KA Smoak, JJ Aloor, J Madenspacher, BA Merrick… - Cell metabolism, 2010 - cell.com
… )2, TLR4, and CD14, utilizing myeloid differentiation primary … MyD88 plays a critical role in
reverse cholesterol transport in … immunity that couples cholesterol trafficking to inflammation …

Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses

L Yvan-Charvet, N Wang, AR Tall - … , thrombosis, and vascular …, 2010 - Am Heart Assoc
cholesterol transport in vivo, 5 and combined deficiency of these transporters in bone
marrow–derived hematopoietic cells leads to severe defects in cholesterol … such as CD14 and MD2…

CD14: Biology and role in the pathogenesis of disease

Z Wu, Z Zhang, Z Lei, P Lei - Cytokine & growth factor reviews, 2019 - Elsevier
… of myeloid cells in a TLR4-independent manner and to transport … in the basic biology of
the CD14 including its structure, binding … potential of targeting the CD14 in related diseases. …

Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids.

B Yu, E Hailman, SD Wright - The Journal of clinical …, 1997 - Am Soc Clin Investig
… Briefly, apo A-1, egg PC, cholesterol, and cholate were mixed at … CD14 binds mammalian
phospholipids that have no … Our results thus suggest that CD14 participates in the transport but …