[HTML][HTML] Chondrocyte death by apoptosis is associated with cartilage matrix degradation
CM Thomas, CJ Fuller, CE Whittles, M Sharif - Osteoarthritis and Cartilage, 2007 - Elsevier
… of chondrocyte apoptosis in equine articular cartilage (AC) specimens and to examine the
relationship between the process of cell death and the degree of cartilage degradation using a …
relationship between the process of cell death and the degree of cartilage degradation using a …
Chondrocyte necrosis and apoptosis in impact damaged articular cartilage
CT Chen, N Burton‐Wurster, C Borden… - Journal of …, 2001 - Wiley Online Library
… We hypothesized that cell death by apoptosis also occurs in cartilage damaged by impact
loads and is related to the structural and metabolic changes found in the injured tissue. …
loads and is related to the structural and metabolic changes found in the injured tissue. …
Chondrocyte death by apoptosis is associated with the initiation and severity of articular cartilage degradation
CM Thomas, CJ Fuller, CE Whittles… - International journal of …, 2011 - Wiley Online Library
… Accordingly, chondrocyte death has been postulated to be a crucial event in the …
cartilage, chondrocyte death occurs by apoptosis or apoptosis-like programmed cell death. …
cartilage, chondrocyte death occurs by apoptosis or apoptosis-like programmed cell death. …
Time, stress, and location dependent chondrocyte death and collagen damage in cyclically loaded articular cartilage
CT Chen, M Bhargava, PM Lin… - Journal of Orthopaedic …, 2003 - Wiley Online Library
… The goal of this study was to investigate chondrocyte … articular cartilage to an extensive
sinusoidal load (similar to the overuse/abnormal use of a joint) would result in chondrocyte death …
sinusoidal load (similar to the overuse/abnormal use of a joint) would result in chondrocyte death …
Role of chondrocyte death and hypocellularity in ageing human articular cartilage and the pathogenesis of osteoarthritis
A Mobasheri - Medical hypotheses, 2002 - Elsevier
… chondrocyte death may represent an important component in the pathogenesis of osteoarthritis
(20). In chondrocytes … The fate of apoptotic bodies in cartilage is uncertain. There are no …
(20). In chondrocytes … The fate of apoptotic bodies in cartilage is uncertain. There are no …
Mechanisms of chondrocyte apoptosis
M Lotz, S Hashimoto, K Kühn - Osteoarthritis and Cartilage, 1999 - Elsevier
… Chondrocyte death may be of pathogenetic significance during … Apoptosis of chondrocytes
in articular cartilage is associated with the destruction of the pericellular matrix and …
in articular cartilage is associated with the destruction of the pericellular matrix and …
Apoptosis and the loss of chondrocyte survival signals contribute to articular cartilage degradation in osteoarthritis
… Additionally some of the components of these pathways may contribute directly or indirectly
to chondrocyte death and cartilage degradation by inducing catabolic processes thereby …
to chondrocyte death and cartilage degradation by inducing catabolic processes thereby …
Cellular events leading to chondrocyte death after cartilage impact injury
DM Green, PC Noble, JS Ahuero… - … : Official Journal of the …, 2006 - Wiley Online Library
… To evaluate the ability of leukocytes to extend the zone of chondrocyte death after impact …
articular cartilage was exposed to an acute impact, approximately half of the chondrocytes died …
articular cartilage was exposed to an acute impact, approximately half of the chondrocytes died …
Chondrocyte-derived apoptotic bodies and calcification of articular cartilage
S Hashimoto, RL Ochs, F Rosen… - Proceedings of the …, 1998 - National Acad Sciences
… Apoptosis represents a physiologic form of cell death that results in removal of apoptotic …
as observed during necrotic cell death (6–8). Articular cartilage has several features that impact …
as observed during necrotic cell death (6–8). Articular cartilage has several features that impact …
Chondrocyte apoptosis: a cause or consequence of osteoarthritis?
… of cell death in articular cartilage. Current ‘gold standard’ for detecting chondrocyte death is
… This article will discuss the recent evidence on chondrocyte death in articular cartilage and …
… This article will discuss the recent evidence on chondrocyte death in articular cartilage and …
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