… Although our study and others have shown significant chondrocyte death and cartilage
degeneration at early time points, there is controversy in the literature regarding the long-term …

… role for the superficial layer of articular cartilage. Combined, these results provide insight …
chondrocyte damage after trauma and emphasize the importance of understanding cartilage …

… locally or stimulate joint-wide cartilage degeneration (1, 4). … to articular cartilage induces
acute chondrocyte necrosis and … cartilage surfaces near sites of extensive chondrocyte death. …

… the Fas receptor pathway can mediate chondrocyte death. There are many important …
chondrocytes. For example, what is the relationship between apoptosis and cartilage degeneration …

… The latter plays an important role in ER stress-induced chondrocyte death. Details … upon
JNK-c-Jun signaling and to induce chondrocyte apoptosis during cartilage degeneration [97]. …

… cartilage degradation. We propose that altered chondrocyte behavior and concomitant cartilage
… Autophagy has been put forward as an alternative cause of chondrocyte cell death in OA …

… 18 while intra-articular hydrogen peroxide caused chondrocyte death in the knee joint of mice
… -induced death of chondrocytes predisposes ageing cartilage to degenerative disorders. …

… death. We hypothesize that post-injury cartilage articulation will lead to increased cartilage
damage. … if subsequent joint articulation exacerbates damage produced by initial injury. We …

… cartilage imaging technique showed that chondrocyte death by diphtheria toxin did not result
in cartilage damage [48]. … whether chondrocyte death itself causes cartilage degradation. …

… that telomere shortening noted in chondrocytes could be due to DNA damage from ROS27, …
that were associated with an increase in susceptibility of chondrocytes to cell death. Further …