… chondrocyte apoptosis is the inducer of cartilage degeneration or a byproduct of cartilage
destruction. Chondrocyte death … chondrocyte death is the main pathogenetic mechanism in OA. …

… chondrocyte death, which recently has been demonstrated after mechanical injury to cartilage
[ 46 ]. Mechanical overload is a risk factor for the development of secondary OA. Because …

… involved in chondrocyte death in the pathogenesis of OA and thus the target for future
therapeutic agents. The relative contribution of NO, TNF , IL-1 and FasL to chondrocyte apoptosis …

… the chronology by which chondrocytes are eliminated during OA pathogenesis, we decided
… During OA pathogenesis, chondrocytes exhibit modifications in their death process in each …

… chondrocyte biology, and, in particular, their death. In this review, we focused the different
kinds of chondrocyte death … Chondrocytes show necrotic features and, occasionally, also …

… of cell death in … of chondrocytes, study of chondrocyte death using Annexin-V-FITC and
propidium iodide double-labeling, caspase-3 activity determination) of human chondrocytes …

… cartilage degradation and chondrocyte death, and different types of cell death in cartilage
have … evidence on chondrocyte death in articular cartilage and its role in pathogenesis of OA. …

… that chondrocyte death does occur at some point in the pathogenesis of OA and that it can
be due to apoptosis, necrosis, or some combination of the two. Chondrocyte death can be …

… which kind of cell death is present in OA cartilage. Our results show that chondrocytes from
OA … features of apoptosis, suggesting that the cells from OA patients die by active cell death. …

… In the present review, we will focus on chondrocyte cell death and its interplay with cartilage
degradation and OA progression. Chondrocyte cell death was reported to occur through …