… , demethylation is targeted to genes by chromatin modification changes. Transcription
factors … In summary, DNA methylation pattern and chromatin structure are found in a dynamic …

Aberrations in the DNA methylation patterns are nowadays recognized as a hallmark of human
cancer One of the most characteristic changes is the hypermethylation of CpG islands of …

… methylation of CpG islands in one X-chromosome in women, which renders these genes
inactive. Finally, although DNA methylation … aim, sometimes DNA methylation accomplishes this …

… and constitutes the DNA methylation profile genome-wide. Since the … DNA methylation
profile is a unique ID of cells, a change in the DNA methylation profile will cause an alteration …

… Understanding the molecular determinants of both normal and abnormal patterns of chromatin
formation and DNA methylation thus holds great promise for our understanding of cancer …

… of methylation losing methyl groups (such as repetitive DNA … DNA methylation patterns
can lead to alterations in gene expression and genome stability through changes in chromatin …

… chromatin structure, DNA methylation also represses transcription. A protein (MeCP) which
binds specifically to methylated DNA … of DNA methylation on both chromatin and transcription. …

… The definition agrees with the central theme of this review that epigenetics is achieved by
DNA methylation and chromatin. Wolffe further placed most emphasis on the transcriptional …

… between DNA methylation and chromatin … chromatin states may dictate genome-wide DNA
methylation patterning. The mammalian DNA methylation machinery – properties of the DNA …

… co-repressors, chromatin remodeling proteins and histone … DNA methylation could then
target the formation of chromatin… of chromatin formation suggest that DNA methylation and …