过去一年中添加的文章,按日期排序

[HTML][HTML] Advances in epigenetic alterations of chronic lymphocytic leukemia: from pathogenesis to treatment

X Zhang, H Wang, Y Zhang, X Wang - Clinical and Experimental Medicine, 2024 - Springer
105 天前 - … CLL in epigenetics such as DNA methylation, histone modification, RNA methylation,
non-coding RNAs, and chromatin remodeling and also highlight … DNA methylation in CLL …

Multi‐omics analysis reveals epigenetically regulated processes and patient classification in lung adenocarcinoma

A Brativnyk, J Ankill, Å Helland… - International Journal of …, 2024 - Wiley Online Library
106 天前 - DNA methylation, histone tail modification, and activity of non-coding RNAs. This
study focuses on DNA methylation, … In this work, we used preprocessed DNA methylation and …

Nrf2 pre‐recruitment at Enhancer 2 is a hallmark of H2O2‐induced epigenetic transcriptional memory in the HMOX1 gene in human umbilical artery endothelial …

I Carrasco‐Wong, G Längst, L Sobrevia… - Journal of Cellular …, 2024 - Wiley Online Library
110 天前 - … Changes in DNA methylation pattern at the HMOX1 promoter were not a hallmark
of this oxidative stress-induced ETM. These data suggest that a pro-oxidant milieu could …

How calorie restriction slows aging: an epigenetic perspective

GM Lim, N Maharajan, GW Cho - Journal of Molecular Medicine, 2024 - Springer
113 天前 - Alterations in DNA methylation are strongly associated with aging [64], which can
be … Epigenetic drift is a term used to describe gradual alterations in DNA methylation patterns …

[HTML][HTML] Altered DNA methylation underlies monocyte dysregulation and immune exhaustion memory in sepsis

BA Caldwell, Y Wu, J Wang, L Li - Cell Reports, 2024 - cell.com
117 天前 - Chromatin alterations, notably via histone modifications, … of DNA methylation
remains poorly understood. Using an ex vivo sepsis model, we show altered DNA methylation

[HTML][HTML] The Alpha-Synuclein Gene (SNCA) is a Genomic Target of Methyl-CpG Binding Protein 2 (MeCP2)—Implications for Parkinson's Disease and Rett Syndrome

I Schmitt, BO Evert, A Sharma, H Khazneh… - Molecular …, 2024 - Springer
119 天前 - … human iPSC-derived neurons by targeted editing of DNA methylation of SNCA
intron 1 [13, 14]. The importance of DNA methylation for a variety of conditions and functions of …

1084 Transcriptomic and epigenetic changes in ovarian high grade serous carcinoma after platinum treatment: results from an in vitro model

G Russo, R Ergasti, MQ Lim, H Mirza, G Giannone… - 2024 - ijgc.bmj.com
120 天前 - DNA methylation data were obtained using with Illumina 950K Infinium …
Methylation analysis of platinumtreated cells revealed enrichment in bivalent chromatin state and …

889 Role of RBBP4 in breast cancer tumorigenesis

N Bouayed, B Abdelmoula - 2024 - ijgc.bmj.com
120 天前 - Introduction/Background Epigenetics, shaping cancer through DNA methylation,
histone modification, chromatin remodeling, and noncoding RNA regulation, plays a key role in …

Abstract 1673 Identification and Characterization of Methylated DNA-Binding Proteins in Xenopus Egg Extracts

S Chakraborty, R Shih, H Funabiki - Journal of Biological Chemistry, 2024 - ASBMB
120 天前 - DNA methylation is an epigenetic mechanism that plays … Alterations in genomic
DNA methylation patterns are … binds or dissociates from methylated DNA in Xenopus laevis egg …

Abstract 1877 A transcriptional memory model for the Epithelial to Mesenchymal Transition

J Grindeland, A Bhattacharya, A Ray… - Journal of Biological …, 2024 - ASBMB
120 天前 - … memory, leading to altered transcriptional responses of a … -seq), chromatin accessibility
(ATAC-seq) and DNA methylation … Mechanistically, DNA methylation, cell signaling, and …