过去一年中添加的文章,按日期排序

Epigenetic regulation in cancer

M Gu, B Ren, Y Fang, J Ren, X Liu, X Wang… - MedComm, 2024 - Wiley Online Library
144 天前 - … , particularly those involving DNA methylation and chromatin modifications. …
DNA methylation, histone modification, chromatin remodeling, and higher-order chromatin

[HTML][HTML] Detecting DNA hydroxymethylation: exploring its role in genome regulation

SM Lee - BMB reports, 2024 - ncbi.nlm.nih.gov
144 天前 - … Epigenetics encompasses changes in gene function or expression that occur
without any alterations to the DNA sequence itself. DNA methylation stands as the first to be …

Evidence of epigenetic landscape shifts in mucopolysaccharidosis IIIB and IVA

V Vargas-López, LF Prada, CJ Alméciga-Díaz - Scientific Reports, 2024 - nature.com
146 天前 - … Multiple studies have reported an association between altered DNA methylation
and aneuploidy, increased chromosomal rearrangements, centromere instability, and …

Functional significance of DNA methylation: epigenetic insights into Sjögren's syndrome

Y Wang, F Riaz, W Wang, J Pu, Y Liang, Z Wu… - Frontiers in …, 2024 - frontiersin.org
147 天前 - … Several investigations have exhibited that RA patients have an altered DNA
methylation pattern in T cells, monocytes, B cells, synovial fibroblasts, and PBMCs (55–57). Similar …

Epigenetic regulation behind plant-microbe interactions

JI Vílchez, S Varotto, HW Jung - Frontiers in Plant Science, 2024 - frontiersin.org
150 天前 - … of this fungal strain led to decreased DNA methylation, a phenomenon known as …
with viroids and assessed RNA-directed DNA methylation (RdDM) to understand the origin of …

Protein arginine methyltransferases (PRMTs): Orchestrators of cancer pathogenesis, immunotherapy dynamics, and drug resistance

Y Gao, C Feng, J Ma, Q Yan - Biochemical pharmacology, 2024 - Elsevier
153 天前 - … PRMTs can contribute to drug resistance through multiple mechanisms, including
the epigenetic regulation of drug efflux pumps, altered DNA damage repair, and modulation …

Molecular alterations in metaphase chromosomes induced by bleomycin

M Urbańska, K Sofińska, M Czaja, K Szymoński… - … Acta Part A: Molecular …, 2024 - Elsevier
153 天前 - … This enabled visualization of changes in the DNA methylation pattern in the spectral
region of 1500–1200 cm −1 resulting from the drug treatment (Fig. 4 D, E) [26]. We observe …

DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos.

G Fanourgakis, L Gaspa-Toneu, PA Komarov… - bioRxiv, 2024 - biorxiv.org
154 天前 - altered sperm chromatin in the formation of embryonic chromatin, we measured …
consequences of the altered DNA methylome in DKO sperm (Supplementary Figure 14E). 455 …

Elucidating the spatial distribution of genomic and epigenetic lamina-associated domains implicated in adipocyte differentiation and hypertrophy

LZ Zeaiter, F Baldini, L Cuneo, F Diab, P Bianchini… - Biophysical …, 2024 - cell.com
155 天前 - DNA methylation and histone modification patterns. Our objective was to elucidate
the potential alterations … in histone acetylation and DNA methylation, that may be involved in …

Remodeling of the nuclear landscapes and epigenome during retro-transformation of neuroblastoma cells mediated by the non-coding RNA NDM29

F Baldini, LZ Zeaiter, L Cuneo, P Bianchini, L Vergani… - Biophysical …, 2024 - cell.com
155 天前 - … We aimed to determine alterations in nuclear and chromatin architecture being …
of chromatin domains. By enzyme-linked immunoassay the overall DNA methylation was …