… A large number of monogenic DD/ID syndromes share chromatin dysregulation as … signs,69
or within the CH1 domain, showing autistic-like features70 usually manifested by a minority …

… These observations place chromatin dysfunction at the top of … Here we undertake a conceptual
investigation of chromatin … of NDD-causing chromatin dysregulation, with a special focus …

… Syndrome (HVDAS), a rare developmental syndrome affecting brain formation and neuronal
functions, involving autism … ASD, its precise role in the syndrome onset has yet to be clarified…

… syndrome of early infantile autism in children aged two to eight years. Todate, the genetic
heterogeneity of this syndrome … A number of pathways dysregulated in ASD, involve chromatin …

… as category 1–3, and syndromic from the SFARI. To … dysregulation, regardless of their
chromatin interactions. Among non-coding DNMs inside DHSs, we selected those not in chromatin …

… elements become transcriptionally dysregulated. In a study of William-Beuren syndrome, in
which … between CNV and dysregulated gene expression through altered chromatin topology. …

… to autism cluster on a relatively limited number of cellular pathways, including chromatin
remodeling. … genes in syndromic autism the Activity-Dependent Neuroprotective Protein (ADNP). …

… regulators, ubiquitin ligases, and other chromatin remodelers, which comprised over half of
that … theme to autism [30]. Our present results indicate that epigenetic dysregulation could …

… These epigenetic modifications, which appear dysregulated in ASD, lead to chromatin … In
addition, the MeCP2 protein, which is lacking in Rett syndrome, binds to Prader-Willi syndrome …

… These pathways are concordant with co-morbidities present in syndromic autism.
Furthermore, overlapping DEG- and DTU-ASD-specific risk genes showed similar enrichment (…