The chromatin landscape of healthy and injured cell types in the human kidney
… nucleus RNA expression and chromatin accessibility, DNA … the chromatin landscape and
gene regulation of the kidney in … kidney’s active, silent, and regulatory accessible chromatin …
gene regulation of the kidney in … kidney’s active, silent, and regulatory accessible chromatin …
Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets
… The human kidney cell type-specific open chromatin landscape showed consistent overlap
with multiple SNPs in multiple cell types (Fig. 6h). Interesting to note that one SNP with strong …
with multiple SNPs in multiple cell types (Fig. 6h). Interesting to note that one SNP with strong …
Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects
… for use on primary human clinical samples to define the chromatin landscape in a … -kidney-specific
classes of chromatin accessibility changes, as well as those associated with chromatin …
classes of chromatin accessibility changes, as well as those associated with chromatin …
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney
… Chromatin accessibility profiling will help to identify distant regulatory regions … chromatin
accessibility can refine our understanding of cell state and function in the mature human kidney. …
accessibility can refine our understanding of cell state and function in the mature human kidney. …
Defining the dynamic chromatin landscape of mouse nephron progenitors
S Hilliard, R Song, H Liu, C Chen, Y Li… - Biology …, 2019 - journals.biologists.com
… In general, our findings are consistent with those of recent scRNA-seq studies of human
kidney development (Lindstrom et al., 2018; Menon et al., 2018; Wang et al., 2018) …
kidney development (Lindstrom et al., 2018; Menon et al., 2018; Wang et al., 2018) …
Chromatin accessibility analysis and architectural profiling of human kidneys reveal key cell types and a regulator of diabetic kidney disease
M Eun, D Kim, SI Shin, HO Yang, KD Kim, SY Choi… - Kidney International, 2024 - Elsevier
… accessibility profiling using healthy and DKD human adult kidneys To analyze the chromatin
landscape of kidney cell types, we performed snATAC-seq using adult kidney tissues from 6 …
landscape of kidney cell types, we performed snATAC-seq using adult kidney tissues from 6 …
Chromatin architecture reveals cell type-specific target genes for kidney disease risk variants
A Duan, H Wang, Y Zhu, Q Wang, J Zhang, Q Hou… - BMC biology, 2021 - Springer
… Our results provide a valuable multi-omics resource on the chromatin landscape of human
kidney tubule cells and establish a bioinformatic pipeline in dissecting functions of kidney …
kidney tubule cells and establish a bioinformatic pipeline in dissecting functions of kidney …
Chromatin dynamics in kidney development and function
W Bechtel-Walz, TB Huber - Cell and tissue research, 2014 - Springer
… be expressed in human kidney mesangial cells and … kidney disease (Komohara et al. 2007).
A recent study links DNA hydroxymethylation and TET gene expression in the mouse kidney …
A recent study links DNA hydroxymethylation and TET gene expression in the mouse kidney …
SETD2 loss perturbs the kidney cancer epigenetic landscape to promote metastasis and engenders actionable dependencies on histone chaperone complexes
… chromatin accessibility to transcription factors and chromatin modifiers, which activates
enhancers and induces gene expression. Accordingly, an integrated ATAC-seq and ChIP–seq …
enhancers and induces gene expression. Accordingly, an integrated ATAC-seq and ChIP–seq …
Unraveling the epigenetic code: human kidney DNA methylation and chromatin dynamics in renal disease development
… human kidney single-cell open chromatin changes in healthy and diseased kidneys, identifying
a large number of open chromatin … (methylation and open chromatin) changes in PT cells …
a large number of open chromatin … (methylation and open chromatin) changes in PT cells …
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