… A breakthrough in our understanding of chromatin folding came from the genome-wide
detection of chromatin loops, contact domains (Rao et al. 2014), and TADs from Hi-C …

… and techniques in the next section, we will describe associated applications in three
subsequent sections organized by genome level, followed by gene folding, and ideas regarding …

… chromatin folding and epigenome. Using polymer physics, we analyze the properties of a
block copolymer model … good agreement with the folding patterns observed in chromosome …

… According to this model, cohesin rings land on chromatin and actively pull out (extrude)
the DNA until they fall off or encounter obstacles such as CTCF bound sites (with the right …

… chromatin … of genome features onto the constructed 3D chromatin model, we show vividly
the close connection between genome properties and the spatial organization of chromatin. …

… grained null models for … folding and dynamics of drosophila genome. Finally, we discuss
our results and their implications in the general context of chromosome modeling and chromatin …

… with mesoscale modeling. We suggest that while the local folding of chromatin can be regulated
… From a combination of 3C data and mesoscale modeling, we suggest that hierarchical …

… model to simulate chromatin structure and dynamics. Starting from one-dimensional genomics
and … We introduce a predictive model to study cell-type specific 3D chromatin folding. This …

… short-range interactions between chromatin domains of the same type may reproduce
the 3D genome folding of several regions (Figure 3b–c). The polymer models could predict …

… We present a Monte Carlo model for genome folding at the 30-nm scale with focus on
linker-histone and nucleosome depletion effects. We find that parameter distributions from …