Strategies for large-scale targeted metabolomics quantification by liquid chromatography-mass spectrometry

J Zhou, Y Yin - Analyst, 2016 - pubs.rsc.org
… the options for large-scale targeted metabolomics study, … LC-MS-based strategies for
large-scale targeted metabolomics … commonly used for large-scale targeted metabolomics …

Large-scale chromatography of proteins

JC Janson, P Hedman - Chromatography, 2005 - Springer
… This is one reason why most large scale applications of the … valuable properties for large
scale chromatographic applications, … Chromatographic media suitable for large scale protein …

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

WB Dunn, D Broadhurst, P Begley, E Zelena… - Nature protocols, 2011 - nature.com
Chromatographymass spectrometry (MS) platforms are … long-term and large-scale
metabolomic studies involving thousands … chromatography–MS (GC-MS) and ultraperformance …

Optimization of large-scale pseudotargeted metabolomics method based on liquid chromatographymass spectrometry

P Luo, P Yin, W Zhang, L Zhou, X Lu, X Lin… - … of Chromatography A, 2016 - Elsevier
… , the final results are promising for a large scale analysis. … are still difficult to achieve in large
scale LC–MS-based … of multiple batches in a large scale metabolomics analysis. We believe …

Largescale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two‐dimensional gel electrophoresis‐mass …

S Hu, Y Xie, P Ramachandran, RR Ogorzalek Loo… - …, 2005 - Wiley Online Library
… , large-scale identification of salivary proteins was demonstrated by using shotgun proteomics
and two-dimensinal gel electrophoresis-mass … liquid chromatography (LC). However, the …

A review of very large scale chromatography

K Jones - Chromatographia, 1988 - Springer
… In the late 1960's high pressure liquid chromatography (HPLC) began … In large scale terms
this division of chromatography had a much smaller hill to climb, and the history of large scale

Basic concepts in Q membrane chromatography for largescale antibody production

JX Zhou, T Tressel - Biotechnology progress, 2006 - Wiley Online Library
… FT-MA can easily save up to 95% of buffer and 66% of process time. A cost comparison …
The cost of 1 m 2 MA is about $2400 but would drop to approximately $2000 at larger scales. …

Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry

RCH De Vos, S Moco, A Lommen, JJB Keurentjes… - Nature protocols, 2007 - nature.com
large-scale untargeted metabolomics of plant tissues, based on reversed phase liquid
chromatography coupled to high-resolution mass … alignment of all extracted mass peaks across all …

Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC− MS/MS) for large-scale protein analysis: the yeast proteome

J Peng, JE Elias, CC Thoreen… - Journal of proteome …, 2003 - ACS Publications
… We have evaluated an offline multidimensional chromatography peptide separation
approach for the large-scale analysis of expressed yeast proteins. We identified 7537 peptides (…

A novel strategy for large-scale metabolomics study by calibrating gross and systematic errors in gas chromatographymass spectrometry

Y Zhao, Z Hao, C Zhao, J Zhao, J Zhang, Y Li… - Analytical …, 2016 - ACS Publications
… Combination of multiple analytical batches in large-scale … Here, we develop a novel correction
strategy for large-scale … by two gas chromatographymass spectrometry instruments. The …