… DNA synthesis, which is likely explained because of a concomitant increase in apoptosis.
Thyrotropin-dependent cell growth and DNA synthesis were … AMP–induced DNA synthesis. We …

Chromosomal instability is a common feature of cancer cells. Several cellular mechanisms …
and structural chromosomal instability in cancer cells, including defects in chromosomal …

… scaffold protein FANCP (otherwise known as SLX4) to cut the DNA on one strand. Next, a
DNA synthesis step is performed by the translesion polymerase FANCV (otherwise known as …

… As described earlier, exposure to DNA synthesis inhibitors promotes centrosome
amplification and chromosome instability in cells lacking functional p53. Considering the high …

… In normal cells, DNA replication and the partitioning of chromosomes are exceptionally …
cycle arrest, DNA repair, and high accuracy of DNA synthesis during DNA replication. Together, …

… of PrimPol in DNA synthesis in S phase cause an accumulation of under-replicated DNA
in M phase and trigger chromosome instability. The under-replicated DNA that accumulates …

… chromosomal instability. Many reports are persuasive in suggesting that spontaneous
chromosomal … be considerable, because spontaneous chromosomal aberrations are not evident in …

… These data reveal that POLQ uniquely extends 3′ DNA tails through template-dependent
DNA synthesis from a primer with minimal base pairing and that the polymerase lacks true TdT…

… Increased chromosome number, fusion, and fragmentation in Rev3L −/− MEFs. We next
looked for evidence of chromosomal instability associated with Rev3L deletion. Chromosome …

… Furthermore, recent studies have shown that the ubiquitin ligase TRAIP promotes replisome
disassembly to drive mitotic DNA synthesis [123,124]. While this mechanism allows the cell …