Fetal-specific DNA methylation ratio permits noninvasive prenatal diagnosis of trisomy 21
EA Papageorgiou, A Karagrigoriou, E Tsaliki… - Nature medicine, 2011 - nature.com
… strategy using the methylated DNA immunoprecipitation (MeDiP) methodology in combination
with real-time quantitative PCR (qPCR) to achieve fetal chromosome dosage assessment, …
with real-time quantitative PCR (qPCR) to achieve fetal chromosome dosage assessment, …
[HTML][HTML] DNA methylation, heterochromatin and epigenetic carcinogens
… Genome instability is evident in tumors and metastatic cancers leading to further aneuploidy,
… The specialized heterochromatinization of the inactive X chromosome occurs by a unique …
… The specialized heterochromatinization of the inactive X chromosome occurs by a unique …
Methylation status of LINE-1 retrotransposon in chromosomal mosaicism during early stages of human embryonic development
SA Vasilyev, EN Tolmacheva, AA Kashevarova… - Molecular Biology, 2015 - Springer
… in aneuploidy distribution over different chromosomes in … forms of numerical chromosomal
abnormalities or with the fact … DNA methylation patterns of metaphase chromosomes in …
abnormalities or with the fact … DNA methylation patterns of metaphase chromosomes in …
“Aberrant” plants in cauliflower: 2. Aneuploidy and global DNA methylation
V Chable, A Rival, T Beulé, J Jahier, F Eber, V Cadot… - Euphytica, 2009 - Springer
… In the “lettuce type” aberrant (Table 1) the chromosomal status ranged from an aneuploidy
… , the aneuploidy status of plants was not taken into account. If we consider DNA methylation …
… , the aneuploidy status of plants was not taken into account. If we consider DNA methylation …
Trans-acting epigenetic effects of chromosomal aneuploidies: lessons from Down syndrome and mouse models
… Thus, results from studying the role of TFBS occupancies in shaping the patterns of DS-DM
may help to consolidate our understanding of the creation of DNA methylation patterns in …
may help to consolidate our understanding of the creation of DNA methylation patterns in …
Microarray-based analysis of methylation status of CpGs in placental DNA and maternal blood DNA–potential new epigenetic biomarkers for cell free fetal DNA-based …
L Hatt, MM Aagaard, J Graakjaer, C Bach, S Sommer… - PLoS …, 2015 - journals.plos.org
… We have analyzed the DNA methylation profiles of … methylation-sensitive restriction enzymes.
We present a list of markers on chromosomes 13, 18 and 21 with a potential for aneuploidy …
We present a list of markers on chromosomes 13, 18 and 21 with a potential for aneuploidy …
The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis
IS Muskens, S Li, T Jackson, N Elliot… - Nature …, 2021 - nature.com
… DNA methylation data excluding chromosomes X, Y… chromosome, this is often not the case
suggesting that epigenetic mechanisms regulate gene expression in the context of aneuploidy…
suggesting that epigenetic mechanisms regulate gene expression in the context of aneuploidy…
Who's afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data
… XY chromosome … chromosome in the context of placental acute chorioamnionitis. Finally,
we provide an annotation of probe types that may be desirable to filter in X and Y chromosome …
we provide an annotation of probe types that may be desirable to filter in X and Y chromosome …
High-resolution analysis of germ cells from men with sex chromosomal aneuploidies reveals normal transcriptome but impaired imprinting
S Laurentino, L Heckmann, S Di Persio, X Li… - Clinical …, 2019 - Springer
… The aim of this study was to investigate the DNA methylation patterns and the transcriptome
of germ cells from Klinefelter patients and compare them to germ cells from men with …
of germ cells from Klinefelter patients and compare them to germ cells from men with …
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia
J Nordlund, CL Bäcklin, P Wahlberg, S Busche… - Genome biology, 2013 - Springer
… methylation leads to X-chromosome inactivation, genomic imprinting, and suppression of
transposable elements. Disruption of DNA methylation patterns is … , such as aneuploidies and …
transposable elements. Disruption of DNA methylation patterns is … , such as aneuploidies and …