… of onabotulinumtoxinA for prevention of headache in those … efficacy and safety of
onabotulinumtoxinA in people with CM … the safety and effectiveness profile of onabotulinumtoxinA …

… The safety and efficacy of onabotulinumtoxinA across these … the unique efficacy and safety
of onabotulinumtoxinA in CM, a … (at least 8 of these days have migraine features). CM affects …

… chronic migraine (10,11). There are limited data on the utilization and safety of
onabotulinumtoxinA for chronic migraine in a … the safety profile of onabotulinumtoxinA for chronic …

… [OL] phase) evaluated the efficacy and safety of onabotulinumtoxinA in CM (≥15 days/…
onabotulinumtoxinA or placebo every 12 weeks for two cycles, followed by onabotulinumtoxinA …

… : This is the second of a pair of studies designed to evaluate the efficacy and safety of
onabotulinumtoxinA (BOTOX®) for prophylaxis of headaches in adults with chronic migraine. …

… Prophylaxis Therapy (PREEMPT) clinical program evaluated the safety and efficacy of
onabotulinumtoxinA in adult patients suffering from CM. As previously reported, the pooled results …

… migraine headache. Previous exploratory trials evaluating the efficacy and safety of
onabotulinumtoxinA … A study of chronic tension-type headache (CTTH) did not observe a …

… Prophylaxis Therapy) clinical program (PREEMPT studies 1 and 2) was conducted to evaluate
the safety and efficacy of onabotulinumtoxinA for headache prophylaxis in adults with CM. …

… symptoms in patients with episodic migraine who had received treatment for … migraine
who were treated with onabotulinumtoxinA had complete or partial response of their migraine …

… Another phase II study (NCT02174861) will assess the long-term (13 months) safety and
efficacy of AMG334 in chronic migraine prevention. It started in June 2014 and should be …