Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain

M De Felice, R Sanoja, R Wang, L Vera-Portocarrero… - Pain, 2011 - journals.lww.com
… the rostral ventromedial medulla (RVM), a site that integrates descending pain modulation
via pain … Thus, expression of nerve injury-induced pain may ultimately depend on descending …

The cellular mechanism by which the rostral ventromedial medulla acts on the spinal cord during chronic pain

Y WeiWei, F WenDi, C Mengru, Y Tuo… - Reviews in the …, 2021 - degruyter.com
… Enhancement of descending facilitation by the RVM is necessary for the occurrence and
maintenance of neuropathic pain. Research on the role of the RVM in regulating the …

[HTML][HTML] Critical role of the rostral ventromedial medulla in early spinal events leading to chronic constriction injury neuropathy in rats

R Sanoja, H Vanegas, V Tortorici - The Journal of Pain, 2008 - Elsevier
… player in neuropathic pain is the so-called “descending pain-… hyperexcitability that characterizes
neuropathic pain is due to … other structures of the rostral ventromedial medulla (RVM) on …

Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain

ML Leong, M Gu, R Speltz-Paiz, EI Stahura… - Journal of …, 2011 - Soc Neuroscience
… of chronic, sometimes intractable, neuropathic pain. Existing … RVM and its neurons in
neuropathic pain, we examined RVM … Our findings suggest that the pathology of neuropathic pain

The role of the rostral ventromedial medulla in stress responses

M Pagliusi Jr, FV Gomes - Brain Sciences, 2023 - mdpi.com
… chronification processes and comorbidity between chronic pain and psychiatric disorders. …
structure of the descending pain modulation system is the rostral ventromedial medulla (RVM), …

Brainstem pain-control circuitry connectivity in chronic neuropathic pain

EP Mills, F Di Pietro, Z Alshelh, CC Peck… - Journal of …, 2018 - Soc Neuroscience
… female patients with chronic neuropathic orofacial pain show increased … the rostral ventromedial
medulla (RVM) and other brainstem pain-modulatory regions, including the ventrolateral

[HTML][HTML] Effect of exercise on µ-opioid receptor expression in the rostral ventromedial medulla in neuropathic pain rat model

YJ Kim, JH Byun, IS Choi - Ann Rehabil Med, 2015 - synapse.koreamed.org
Neuropathic pain is chronic in most patients [… neuropathic pain and verify whether regular
treadmill exercise alters the µ-opioid receptor (MOR) expression in RVM in a neuropathic pain

Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain

SE Burgess, LR Gardell, MH Ossipov… - Journal of …, 2002 - Soc Neuroscience
… in the rostral ventromedial medulla (RVM) in the initiation and maintenance of experimental
neuropathic painPersistent spontaneous afferent input also results in sensitization of spinal …

Activation of the Mammalian Target of Rapamycin in the Rostral Ventromedial Medulla Contributes to the Maintenance of Nerve Injury‐Induced Neuropathic Pain in …

J Wang, DY Feng, ZH Li, B Feng, H Zhang… - Neural …, 2015 - Wiley Online Library
rostral ventromedial medulla (RVM) is an important relay region that contributes to the
descending pain … to the development of persistent pain induced by tissue and nerve injury [3]. …

… within the rodent anterior cingulate cortex and rostral ventromedial medulla reveal separable modulation of affective and sensory qualities of acute or chronic pain

L Gomtsian, K Bannister, N Eyde, D Robles… - Pain, 2018 - journals.lww.com
… selective modulation of affective qualities of neuropathic pain in rodents, but whether such
… the rostral ventromedial medulla (RVM), and pain behaviors in naive, sham, or spinal nerve