… factors that trigger PSC activation within the context of chronic pancreatitis. These factors …
, we explore the regulatory factors that play significant roles during PSC activation, such as …

… of fibrosis by regulating chronic pancreatitis-related cytokines 95 . Above all, studies have
shown that ERK pathway acts on the migration, activation and matrix synthesis of PSCs 96 . …

… pancreatic fibrogenesis in chronic pancreatitis and in the desmoplastic reaction of pancreatic
… Thus, the TGF-β superfamily plays an important role in the regulation of PSC activation and …

… the activation of pancreatic stellate cells in chronic pancreatitis and development of … activation
is not regulated by neutrophils, whereas later activation of trypsinogen during pancreatitis …

… of matrix remodeling and the regulatory cytokine TGF-β1 that… prevent the pancreas from
activating the pancreatic enzyme … in activation of enzyme cascade and subsequent pancreatic …

… patients with severe acute pancreatitis and which may lead to chronic pancreatitis. Over the
… an unfolded protein response, which activates the immune system independently of trypsin …

… Chronic pancreatitis (CP) is a dynamic inflammatory process which is … identification and
characterization of pancreatic stellate cells (… activated receptor ligand regulate phagocytosis by …

… the pathobiology of chronic pancreatitis (CP) and pancreatic ductal adenocarcinoma (PDAC).
Activated pancreatic myofibroblasts (PMFs) … Extracellular signals regulating PMF activation …

… European patients with nonalcoholic chronic pancreatitis using targeted … , global risk gene
for chronic pancreatitis; it contributes to … The channel is activated by phosphoinositol lipids and …

… We show sustained up-regulation of unfolded protein response components ATF4, CHOP,
GRP78, and XBP1 in CP. Overexpression of GRP78 and ATF4 in human CP confirmed the …