[HTML][HTML] Targeting pancreatic stellate cells in chronic pancreatitis: Focus on therapeutic drugs and natural compounds

Y Wu, C Zhang, M Guo, W Hu, Y Qiu, M Li… - Frontiers in …, 2022 - frontiersin.org
… More research on specifically targeting PSCs would help facilitate the development of novel
therapies for pancreatic fibrosis. Notably, using natural compounds from medicinal plants as …

[HTML][HTML] Selective phytochemicals targeting pancreatic stellate cells as new anti-fibrotic agents for chronic pancreatitis and pancreatic cancer

P Ramakrishnan, WM Loh, SCB Gopinath… - … Pharmaceutica Sinica B, 2020 - Elsevier
… Application of phytochemicals as new anti-fibrotic agents in treating chronic pancreatitis and
pancreatitis cancer In recent decades, plant-based/herbal constituents and natural products …

[PDF][PDF] The pathogenesis of chronic pancreatitis

JM Braganza - QJM: An International Journal of Medicine, 1996 - Citeseer
… during human pancreas grafting invariably damages … pancreatitis which may then evolve
into chronic pancreatitis.Animal models to simulate this and other settings of acute pancreatitis

[HTML][HTML] Oxidative stress and inflammatory signaling in cerulein pancreatitis

JH Yu, H Kim - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
… cascade in acute pancreatitis. Therapeutic studies have shown that antioxidants and natural
compounds can have beneficial effects for patients with pancreatitis and can also influence …

[HTML][HTML] Antioxidative phytoceuticals to ameliorate pancreatitis in animal models: An answer from nature

JM Park, S Lee, MK Chung, SH Kwon… - World journal of …, 2014 - ncbi.nlm.nih.gov
… To test the hypothesis that preventive apoptosis execution would limit the propagation of
necro-inflammations in pancreatitis, our group[20] investigated the ability of natural products to …

A framework for the aetiogenesis of chronic pancreatitis

JM Braganza - Digestion, 1998 - karger.com
Chronic pancreatitis is a progressive and generally painful … concept wherein the
pancreatic acinar cell is regarded as … The natural history of chronic pancreatitis is well known, …

Phytochemicals with protective effects against acute pancreatitis: a review of recent literature

Y Tang, M Sun, Z Liu - Pharmaceutical Biology, 2022 - Taylor & Francis
… Isoliquiritigenin (ISL) is a natural compound derived from various edible plants, eg, …
Curcumin, a natural polyphenolic compound extracted from the perennial herb Curcuma longa L. (…

Natural compounds flavonoids as modulators of inflammasomes in chronic diseases

BA Owona, WA Abia, PF Moundipa - International immunopharmacology, 2020 - Elsevier
natural compounds to disease treatment has become a unique trend in clinical research.
Flavonoids, a group of polyphenolic compounds … and progression of chronic disorders including …

[HTML][HTML] Pancreatic Stellate Cells and the Targeted Therapeutic Strategies in Chronic Pancreatitis

M Chang, W Chen, R Xia, Y Peng, P Niu, H Fan - Molecules, 2023 - mdpi.com
… ingredients and natural chemicals have been widely used as complementary and alternative
medicines to extend lifespan and treat diseases [51]. The natural compounds in plants also …

[HTML][HTML] Animal models for investigating chronic pancreatitis

AA Aghdassi, J Mayerle, S Christochowitz… - Fibrogenesis & tissue …, 2011 - Springer
… development of chronic pancreatitis. Despite advances in the diagnosis of chronic pancreatitis,
… are mostly restricted to relieving symptoms rather than changing the natural history [6, 7]. …