Distinct DNA methylation changes highly correlated with chronological age in the human brain

DG Hernandez, MA Nalls, JR Gibbs… - Human molecular …, 2011 - academic.oup.com
… between the ages of 1 … DNA methylation and chronological age. The majority of these loci
are within CpG islands and there is a positive correlation between age and DNA methylation

Chronological age prediction: developmental evaluation of DNA methylation-based machine learning models

H Fan, Q Xie, Z Zhang, J Wang, X Chen… - … in Bioengineering and …, 2022 - frontiersin.org
… datasets according to different genders and chronological ages, and we evaluated the model
… to find the best-performing ML model of CHS to estimate the chronological ages in practice. …

Inferring chronological age from DNA methylation patterns of human teeth

C Giuliani, E Cilli, MG Bacalini… - American Journal of …, 2016 - Wiley Online Library
… for the estimation of individual's age even more urgent for … DNA studies. Therefore, the aim
of this study is to identify genomic regions whose DNA methylation level correlates with age

Improved prediction of chronological age from DNA methylation limits it as a biomarker of ageing

Q Zhang, CL Vallerga, RM Walker, T Lin, AK Henders… - bioRxiv, 2018 - biorxiv.org
chronological age in those samples could be effectively captured by all the DNA methylation
… training set a near-perfect predictor of chronological age can be built. Our results showing …

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
chronological age of the donor. Together, these observations point to the existence of two
phenomena that both contribute to age-related DNA methylation … of DNA methylation as well …

DNA methylation-based age clocks: From age prediction to age reversion

R Noroozi, S Ghafouri-Fard, A Pisarek… - Ageing Research …, 2021 - Elsevier
… between DNAm age and chronological age, and … DNA methylation age regressed on
chronological age. Positive EAA refers to a higher estimated age than expected chronological age

DNA methylation correlates of chronological age in diverse human tissue types

N Jain, JL Li, L Tong, F Jasmine, MG Kibriya… - Epigenetics & …, 2024 - Springer
… of chronological age with DNA methylation (DNAm) in whole blood has been extensively
studied, the tissue-specificity of age-… Studies investigating the association of age with DNAm in …

Blood-based epigenetic estimators of chronological age in human adults using DNA methylation data from the Illumina MethylationEPIC array

Y Lee, KL Haftorn, WRP Denault, HE Nustad, CM Page… - BMC genomics, 2020 - Springer
chronological age on DNAm levels (chronological age = … that displays chronological age
on the x-axis and DNAm age on … that DNAm age is overestimated in the oldest age group and …

DNA methylation of decedent blood samples to estimate the chronological age of human remains

Y Anaya, P Yew, KA Roberts, WR Hardy - International Journal of Legal …, 2021 - Springer
DNA methylation and chronological age. A total of 232 of 264 sample DNA extracts provided
percent methylation … The methylation analysis of 32 samples failed for at least one locus (…

DNA methylation in ELOVL2 and C1orf132 correctly predicted chronological age of individuals from three disease groups

M Spólnicka, E Pośpiech, B Pepłońska… - International journal of …, 2018 - Springer
… prediction accuracy parameters and thus perfectly fit with our aim to evaluate potential
dysregulation of DNA methylation of markers used for chronological age prediction. …