Cinnamic acid derivatives as inhibitors of oncogenic protein kinases–structure, mechanisms and biomedical effects
M Mielecki, B Lesyng - Current Medicinal Chemistry, 2016 - ingentaconnect.com
… Cinnamic acid derivatives may affect … cinnamic acid with protein kinases (ERBB1, ERBB2,
JAK2, ABL, RIO1, CK2, PIM1, PIM2, mTOR, RSK2) as the crucial components of the signaling …
JAK2, ABL, RIO1, CK2, PIM1, PIM2, mTOR, RSK2) as the crucial components of the signaling …
[HTML][HTML] Cinnamic acid (CINN) induces apoptosis and proliferation in human nasopharyngeal carcinoma cells
G Qi, J Chen, C Shi, Y Wang, S Mi, W Shao… - Cellular Physiology and …, 2016 - karger.com
… Cinnamic acid (CINN, also known as beta-phenylacrylic acid) is the main ingredient of the …
factor that regulates growth-related signal transduction pathways, cell proliferation, apoptosis, …
factor that regulates growth-related signal transduction pathways, cell proliferation, apoptosis, …
Propolis cinnamic acid derivatives induce apoptosis through both extrinsic and intrinsic apoptosis signaling pathways and modulate of miRNA expression
M Kumazaki, H Shinohara, K Taniguchi, N Yamada… - Phytomedicine, 2014 - Elsevier
… propolis cinnamic acid derivatives Artepilin C, Baccharin, and Drupanin induced apoptotic
cell death through both extrinsic and intrinsic apoptosis signal transduction pathways when …
cell death through both extrinsic and intrinsic apoptosis signal transduction pathways when …
[HTML][HTML] Cinnamic acid and its derivatives: mechanisms for prevention and management of diabetes and its complications
S Adisakwattana - Nutrients, 2017 - mdpi.com
… Cinnamic acid and its derivatives (Figure 1), naturally occurring … pathway where phenylalanine
and tyrosine are two precursor molecules [12,13]. Biosynthetic pathway of cinnamic acids …
and tyrosine are two precursor molecules [12,13]. Biosynthetic pathway of cinnamic acids …
Cinnamic acid preserves against myocardial ischemia/reperfusion injury via suppression of NLRP3/Caspase-1/GSDMD signaling pathway
F Luan, Z Rao, L Peng, Z Lei, J Zeng, X Peng, R Yang… - Phytomedicine, 2022 - Elsevier
Background Cinnamic acid (CA) is an active organic acid compound extracted from Cinnamomi
ramulus that has various biological activities. There is growing studies have shown that …
ramulus that has various biological activities. There is growing studies have shown that …
… , synthesis and evaluation of ursodeoxycholic acid-cinnamic acid hybrids as potential anti-inflammatory agents by inhibiting Akt/NF-κB and MAPK signaling pathways
X Li, Y Hu, B He, L Li, Y Tian, Y Xiao, H Shang… - European Journal of …, 2023 - Elsevier
… of cinnamic acid and the hybrid derivatives of cinnamic acid. … Thus, in this study, a series
of UDCA-cinnamic acid hybrids … as a bridge connecting UDCA and cinnamic acid. The anti-…
of UDCA-cinnamic acid hybrids … as a bridge connecting UDCA and cinnamic acid. The anti-…
Design, synthesis, and activity study of cinnamic acid derivatives as potent antineuroinflammatory agents
S Huang, W Liu, Y Li, K Zhang, X Zheng… - ACS Chemical …, 2021 - ACS Publications
… to design and synthesize 24 cinnamic acid derivatives containing D-amino acid or peptides,
with … Furthermore, the antineuroinflammatory capacity of the cinnamic acid derivatives was …
with … Furthermore, the antineuroinflammatory capacity of the cinnamic acid derivatives was …
Cinnamic hydroxamic acid inhibits the proliferation of gastric cancer cells via upregulation of miR 145 expression and down-regulation of P13K/Akt signaling pathway
SP Li, SM Hu - Tropical Journal of Pharmaceutical Research, 2020 - ajol.info
… The initiation of GC involves several signaling pathways and abnormal gene expression
patterns which are often accompanied by inactivation of antioncogenes and activation of …
patterns which are often accompanied by inactivation of antioncogenes and activation of …
[HTML][HTML] Trans-Cinnamic Acid Stimulates White Fat Browning and Activates Brown Adipocytes
NH Kang, S Mukherjee, JW Yun - Nutrients, 2019 - mdpi.com
… in adipocytes, we evaluated the activity of trans-cinnamic acid (tCA), a class of cinnamon …
by activating the β3-AR and AMPK signaling pathways. tCA can induce browning, increase …
by activating the β3-AR and AMPK signaling pathways. tCA can induce browning, increase …
[HTML][HTML] Cinnamic acid nanoparticles modulate redox signal and inflammatory response in gamma irradiated rats suffering from acute pancreatitis
OAR Abozaid, FSM Moawed, ESA Ahmed… - … et Biophysica Acta (BBA …, 2020 - Elsevier
… of Cinnamic acid nanoparticles (CA-NPs) as a modulator for the redox signaling pathway …
, NF-κB, and ASK1/MAPK signaling pathways. Collectively, the current findings showed that CA…
, NF-κB, and ASK1/MAPK signaling pathways. Collectively, the current findings showed that CA…
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