… vivo, at least partly, by suppressing the PI3K/AKT signalling pathway. This study revealed
the function of a novel circular RNA, circ-IGF1R, and may provide new insights and therapeutic …

… This study investigated the regulatory effects of circular RNA (… The expression of IGF1R in
EC tissues was significantly … IGF1R expression and activating PI3K/Akt signaling pathway. Also…

… of circ-IGF1R; circ-IGF1R may, thus, play a carcinogenic role in HCC by activating the PI3K/AKT
signaling pathway… time that circ-IGF1R can inhibit the Wnt/β-catenin pathway through the …

… (miRNAs) and circular RNAs (circRNAs), are … IGF1R to regulate the PI3K/AKT signaling
pathway. A novel circRILPL1 was identified that could sponge miR-145 and is related to AKT …

… We investigated the role of a circular ribonucleic acid, circDiaph3, in the proliferation and …
we found that PI3K, AKT, mTOR and insulin-like growth factor 1 signaling pathway (IGF1R) and …

… Multiple lines of evidence have demonstrated that circular RNAs (circRNAs) play … IGF1R
mRNA expression, thus promoting SCLC progression by activating the PI3K/AKT pathway…

… Furthermore, accruing studies suggest IGF1R plays an oncogenic role in … and IGF1R.
Therefore, we hypothesized circ_0000517 could serve as a ceRNA for miR-326 to target IGF1R to …

… Accumulating research findings have shown that circular RNAs (… pathway of the
hsa_circ_0003596/miR-502-5p/IGF1R … -502-5p/IGF1R/PI3K/AKT signaling axis in ccRCC …

… addition, IGF1R mainly performs its function through the PI3K/Akt/mTOR signaling pathway
[… up-regulate IGF1R expression and activate the PI3K/Akt/mTOR pathway to promote GC …

… the typical circular form … IGF1R evokes dimerization of IGF1R and autophosphorylation of
specific tyrosine residues, which activate the PI3K/AKT and MAPK/ERK1/2 signaling pathways …